摘要
目的:采用病例对照研究的方法,利用实验室检测前白蛋白、血红蛋白、人体测量学指标,对急性脑卒中患者营养状况做出迅速、准确的判断,同时采用NIHSS、改良Rankin量表的测定来判定与预后的关系。方法:共搜集133例符合入选标准病例,依据营养状况分为营养正常组和营养不良组,入院时及入院后2周完成体重指数(BMI)、三头肌皮褶厚度(TSF)、上臂中点围(MAC)的测量、美国国立卫生院神经功能缺损评分(NIHSS)、改良Rankin量表的评分及采集血液做血清前白蛋白、血红蛋白的测定。结果:卒中后营养不良患者中重度残疾(Rankin评分4~5分)的患者为45.6%,而正常营养状态患者为12.3%;卒中后低前白蛋白血症中重度残疾患者为50.8%,显著高于正常血清前白蛋白患者的8.8%;卒中后低血红蛋白重度残疾患者为33.3%,而正常血红蛋白患者为28.7%。结论:卒中后营养不良、低前白蛋白血症与残障程度有关,低血红蛋白与残障程度无关。
Objective:To determine the nutritional status of patients with acute stroke by the levels of prealbumin,hemoglobin and anthropometric indexes in a case-control study.And to detect the relationships between those biomarkers and prognosis of the disease by NIHSS,as well as modified Rankin Scale Determination.Methods: According to the nutritional status,133 patients with acute stroke were divided into normal nutrition group and malnutrition group.Body mass index(BMI),triceps skinfold thickness(TSF),mid-upper arm circumference(MAC),NIHSS,modified rankin scale score,and the serum levels of prealbumin,hemoglobin were measured on admission and two weeks after admission.Results: After stroke,the severely disabled in malnutrition group and normal nutrition group were 45.6 % and 12.3 %,respectively.The severely disabled in patients with hypoalbuminemia were significantly more than in patients with normal prealbumin level,the severe disability rates in two groups were 50.8 % and 8.8 %,respectively.And the severely disabled in patients with low hemoglobin and patients with normal hemoglobin level were 33.3 % and 28.7 %,respectively.Conclusion: After stroke,malnutrition and hypoalbuminemia in patients are correlated with the degree of disability,while low hemoglobin is not associated with the degree of disability.
出处
《包头医学院学报》
CAS
2011年第2期38-39,43,共3页
Journal of Baotou Medical College