摘要
目的对65岁以上老年消化性溃疡患者进行幽门螺杆菌和超敏C反应蛋白检测,并随访观察,统计脑梗死发生情况。方法检测患者的幽门螺杆菌(Hp)和超敏C反应蛋白(hsCRP)水平,分为Hp阳性组和Hp阴性组。正规治疗半年后复测,Hp阳性组再分为Hp未清除组和Hp清除组,并同步监测超敏C反应蛋白情况,之后作为期3年的随访,观察其脑梗死发生情况。结果 Hp阳性组hsCRP水平均较Hp阴性组高(P<0.01)。Hp未清除组hsCRP水平均较Hp清除组高(P<0.01);而Hp清除组与Hp阴性组比较无明显差异(P>0.05)。脑梗死发生率,Hp未清除组较Hp清除组高(P<0.01);而Hp清除组与Hp阴性组比较无明显差异(P>0.05)。结论老年消化性溃疡患者HP阳性者伴有hsCRP水平增高,Hp感染可能系老年脑梗死的一个独立危险因素。
Objective Test the level of HP and hsCRP in patients with peptic ulcer which over the age of 65, then follow - up observe the statistical occurrence of cerebral infarction. Methotis Detect the level of Hp and hsCRP in patients, which were divided into Hp - positive group and the Hp negative group. Six months later, retest them and divided Hp - positive group into Hp no clear group and Hp clear group. By a period of 3 years of follow - up, observed the occurrence of cerebral infarction. Result The hsCRP level of Hp- positive group was higher than in Hp negative group （P〈0.01）. The level of hsCRP levels of not clear group was higher than in of Hp clear group （P〈 0.01）, while there is no significant difference in Hp clear group and Hp negative group （P 〉0.05）. The incidence of cerebral infarction were higher in Hp not clear group than Hp clearance group （P〈0.01）, while there is no significant difference in Hp clear group and Hp negative group （P 〉 0.05）. Conclusions Elderly peptic ulcer patients with HP - positive associated with hsCRP levels increased, Hp infection may be an independent risk factor for cerebral infarction.
出处
《实用临床医药杂志》
CAS
2011年第5期19-20,29,共3页
Journal of Clinical Medicine in Practice
关键词
老年
消化性溃疡
幽门螺杆菌
C反应蛋白
脑梗死
aged
peptic ulcer
Helicobacter pylori
C- reactive protein
cerebral infarction
