摘要
目的:分析宫血宁胶囊预防放置IUD致子宫异常出血的效果。方法:应用meta分析方法的固定效应模型,对国内1990~2010年采用宫血宁胶囊预防放置IUD致出血副反应,并以空白或安慰剂对照的随机分组研究进行定量合并分析。结果:治疗组1168例患者中87例经量增多或经期延长,对照组1168例患者中392例经量增多或经期延长。合并优势比(OR)=6.79,95%置信区间(CI)为5.25~8.78,两者间差异有统计学意义(合并效果检验统计量Z=14.58,P<0.001)。结论:宫血宁胶囊预防放置IUD出血副反应的效果肯定,可以显著减少经量增多和经期延长的发生。
Objective:To explore effects of Gongxuening Capsules on preventing abnormal uterine bleeding after intrauterine device(IUD)insertion.Methods:A fixed-effect model of meta-analysis of six literatures published between 1990 and 2010,involving in a randomized placebo-controlled trail(or with blank as the control),was used to evaluate effects of Gongxuening Capsules.Results:Eighty-seven of 1 168 women using Gongxuening Capsules and 392 women in the control group experienced menorrhagia or menostaxis,showing a statistical significance(Z=14.58,P0.001).The total odds ratio was 6.79(95%CI:5.25,8.78).Conclusion:Gongxuening Capsules can significantly reduce the incidence of menorrhagia and menostaxis.
出处
《中国计划生育学杂志》
北大核心
2011年第4期202-205,共4页
Chinese Journal of Family Planning
关键词
宫内节育器
出血
宫血宁
Meta分析
Intrauterine device
Bleeding
Gongxuening Capsules
Meta analysis