摘要
为探讨血中β2-微球蛋白变化对评价老年高血压病患者肾功能损害的意义,用放射免疫法检测高血压病组(41例)及对照组(61例)血β2-微球蛋白(β2-MG),同时测定尿素氮(BuN)及肌酐(Cr),进行统计分析。结果 ,高血压病组患者血β2-微球蛋白水平明显高于对照组(P=0.014);而BuN、Cr两组间差异无统计学意义。血β2-MG可作为评价高血压病患者肾功能早期损害的指标,对患者病情的评价、预后及指导用药有一定的临床意义。
To study the relationship between theβ2-MG and patients with hypertension.And to evaluate for early renal dysfunction in Senile hypertension patients.The serumβ_2M were measured by RIA in go patients（41） with hypertension,and 61 patients contrals.Renogram urine tontine and blood creatinine atinine were made at the same time.The results showed that concentrations of serumβ_2M was higher than control group（P=0.014）,hence these criteria of serumβ_2M RIA are sensitive for early renal domage in hypertension.This result presents available evidence regarding the benefits of treatment and control of blood pressure in patients with resistant hypertension and offers a critical evaluation of existing data in this field.于中国论文
出处
《疾病监测与控制》
2011年第4期197-198,共2页
Journal of Diseases Monitor and Control
基金
重庆市科委自然科学基金(编号:CSTC
2006BB5044)
重庆医科大学校办课题(编号:QD200535)资助
