摘要
目的：分析阿德福韦在治疗肝功能衰竭中的体会。方法：对2008年2月～2010年1月收治的11例应用拉米夫定耐药而出现肝功能衰竭的慢性乙型肝炎患者，经改为或联用阿德福韦治疗。结果：11例患者经治疗后病情均好转。病毒指标、生化指标、肝功能等均有改善。其中有4例出现恶心、胀气等消化道症状，经对症处理后有所缓解。结论：阿德福韦作为新一代的抗HBV药物，服用后乙型肝炎病毒发生变异少，在拉米夫定治疗出现病毒变异后应用阿德福韦仍有效。
Objective： To analysis the experience on treating liver failure with adefovir therapy. Methods： 11 cases were applied lamivudine resistance and appear liver failure of chronic hepatitis B during February 2008-2010 January treated with adefovir therapy. Results： The condition of 11 patients after treatment were improved. Virus index, biochemical index, liver function were improved. There were 4 cases of nausea, bilge gas, etc, the enteron symptom after received alimta eased, 4 cases in which nausea, flatulence and other gastrointestinal symptoms eased after symptomatic treatment. Conclusions： Adefovir as a new generation of drug re istance HBV, after take hepatitis B virus could mutate into a small, lamivudine therapy appear virus after application adefovir is still effective.
出处
《中医临床研究》
2011年第6期41-41,共1页
Clinical Journal Of Chinese Medicine
