摘要
目的 评价内镜下尼龙绳结扎技术治疗上消化道黏膜下肿瘤的临床疗效与安全性.方法 选择位于食管、胃、十二指肠的黏膜下肿瘤,采用内镜下尼龙绳结扎治疗,包括直接结扎、透明帽辅助结扎、双通道内镜结扎以及联合黏膜下剥离术（ESD）结扎.术后内镜随访,评价治疗效果与安全性.结果 自2006年6月至2008年12月共入选128例黏膜下肿瘤患者,食管28例,胃82例,十二指肠18例.3例采用直接结扎法,105例采用透明帽辅助结扎法,8例采用双通道内镜结扎法,12例联合ESD结扎.111例患者接受内镜随访,16例病灶（14.4%）较前明显缩小,16例（14.4%）尼龙绳未脱落,其余71例（63.9%）病人病灶完全消失,治疗有效率为92.8%.均未出现迟发性穿孔、出血等并发症.结论 内镜下尼龙绳结扎联合其他辅助方法治疗上消化道黏膜下肿瘤是安全及有效的.
Objective To evaluate the clinical efficacy and safety of 4 types of endoscopic nylon ligation in the treatment of submucosal tumors in upper gastrointestinal tract. Methods Those with submu- cosal tumors located in esophagus, stomach or duodenum were enrolled in the study. All patients were trea- ted with endoscopic nylon ligation, which included direct ligation, ligation with a transparent cap, ligation with dual-channel endoscope, and ligation in combination with endoscopic submucosal dissection （ESD）. The patients were followed up endoscopically for evaluation of efficacy and safety of the procedures. Results A total of 128 patients were recruited into the present study from June 2006 to December 2008. The tumors were in esophagus in 28 patients, in stomach in 82 and in duodenum in 18. Direct ligation was applied in 3 patients, ligation with a transparent cap in 105, ligation with a dual-channel endoscope in 8, and ligation plus ESD in 12. Endoscopic follow-up was completed in 111 patients. Reduced lesion size was observed in 16 patients （ I4.4% ） , residue nylon in 16 （ 14. 4% ） and no lesion in 71 others （63.9%）. The overall ef- fective rate was 92.8%. No delayed perforation or bleeding occurred. Conclusion Endoscopic ligation with nylon thread in combination with other assistant approaches is effective and safe for the treatment of submuco- sal tumors in upper gastrointestinal tract.
出处
《中华消化内镜杂志》
北大核心
2010年第11期581-584,共4页
Chinese Journal of Digestive Endoscopy
关键词
胃肠肿瘤
尼龙绳结扎术
内镜黏膜下剥离术
Gastrointestinal neoplasms
Nylon thread ligation
Endoscopic submucosal dissection
