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中医药治疗阿尔茨海默病临床试验文献评价 被引量:10

literature appraisement of clinical trials in TCM treatment of Alzheimer's disease
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摘要 目的:评价中医药治疗阿尔茨海默病临床试验文献的质量。方法:检索1997-2006年国内生物医学期刊和会议论著发表的有关中医药治疗阿尔茨海默病的临床试验文献,收集文献信息,进行描述性分析和一致性检验。结果:共纳入病例数大于10例的临床文献201篇。对文献的一般情况、研究方法情况、研究分组情况、中医药辨证分型及证候分类、药方剂型、药物信息、干预方式、疗效评价标准、样本量等几个方面进行分析。结论:中医药治疗阿尔茨海默病的临床文献质量呈增高趋势,设计日趋严谨。但亦有不足,当根据中医药的特色,规范严谨的制定临床方案,使临床研究结果准确可靠,使中医药治疗阿尔茨海默病的结果得到广泛认可。 Objective:To evaluate the quality of medical treatment on Alzheimer's Disease Clinical Trials.Methods:Retrieving the Chinese medicine treatment of Alzheimer's disease clinical trial literature in biomedical journals from 1997 to 2006.Collecting literature information,carrying descriptive analysis and consistency check.Results:Adopting 201 articles of clinical literature in which the number of case are more than 10 to analyze general literature,research methods,research grouping,TCM Syndrome Differentiation type and classification,prescription dosage,drug information,intervention,criteria of efficacy evaluation,sample size,and several other aspects.Conclusion:Medical treatment of Alzheimer's disease showed an increasing trend in the quality of the clinical literature,stringent experimental design.Rigorous specifications of the clinical program should be developed based on the characteristics of Chinese medicine so that clinical research will be accurate and reliable,and the results of medical treatment of Alzheimer's disease is widely recognized.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2011年第4期788-791,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家"十一五"科技支撑计划子课题(No.2006BAI04A21) 国家"十一五"科技支撑计划子课题(No.2006BAI08B02-03) 中国中医科学院基本科研业务费自主选题项目(No.Z02042)~~
关键词 中医药 阿尔茨海默病 临床试验 文献质量评价 TCM Alzheimer's disease Clinical trial Assessment of study quality
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