摘要
目的 研究暴发型伤寒患者血小板 PLT、MPV、PCT和 PDW四项参数及血小板聚集率的变化及其临床意义。方法 分别对伤寒急性期和恢复期患者用 Mematil 2 0型血细胞计数仪检测血小板四项参数并同时检测血小板 1min、 5 min和最大聚集率 ,并与正常对照组比较。结果 伤寒急性期各项参数及血小板聚集率均明显降低 ,与对照组比较有显著性差异 ( P<0 0 5或 P<0 0 1) ,而进入恢复期后又恢复正常。结论 伤寒所致血小板减少可能主要与骨髓抑制有关 ,而伤寒所致血小板四项参数及血小板聚集率的改变与病情相平行 ,对判断疾病的预后有一定价值。
objective To study the changes and clinical implications of platelet count (PLT),mean platelet volume (MPV),plateletcytocrit(PCT),platelet distribution width (PDW) and plalelet aggregation rate in fulminant typhoid fever.Methods All data from 28 patients were deteccted with Hematil 20 Hematology Analyzer at both acute and recovery stage and were compared with those in control group.Results ln acute stage,all data decreased apparently,being different significantly from those in control group (( P <0 05, P <0 01);but in recovery stage,these data turned to be normal.Conclusion Platelet decrease caused by typhoid fever may be related to myeloid in hibition.Changes of platelet parameters may be benefit for predicting the prognosis of fulminant typhoid fever.
出处
《临床内科杂志》
CAS
1999年第5期257-258,共2页
Journal of Clinical Internal Medicine
关键词
伤寒
血小板聚集
血小板计数
Typhoid fever platelet aggregation
platelet count
