摘要
目的:监测革兰阴性细菌耐药状况,为指导临床抗生素合理应用提供依据。方法:对从临床各类送检标本进行培养分离鉴定,对分离到的革兰阴性菌采用K-B法进行抗生素敏感实验。结果:共分离到302株革兰阴性细菌,其中分离第一位的是大肠埃希菌(95株),其次是肺炎克雷伯(40株)、铜绿假单胞菌(35株)和鲍曼不动杆菌(26株)。大肠埃希菌耐药性比较严重,对喹诺酮中的环丙沙星和三代头孢菌素耐药性都在60%以上,大肠埃希菌和肺炎克雷伯菌产ESBLs比率分别为64.8%和41.3%。铜绿假单胞菌对碳青霉烯类的敏感性仍保持在80%以上,鲍曼不动杆菌对大多数药物敏感率低于50%。结论:细菌耐药情况普遍存在,应引起医疗单位和管理部门的高度重视。
Objective To monitor gram-negtive bacteria resistant situation in 2010,to offer evidence for clinical reasonable antibiotics usage.Methods All clinical secimas were isolated and cultured and identified in 2010.Positive bacteria use K-B doing drug-sensitive test according to CLSI 2009.Results 302 strains bacteria were isolate.The first frequent bacteria was E.coli(95 strains).Klebsiella pneumoniae(64 strains),Pseudomonas.aeruginosa(45 strains),Acinetobacter baumannii(36 strains),respectively.The drug-resistance of E.coli was very high,resented by their resistance to Ciprofioxacin and the third cephalothin antibiotics was over 60%.ESBLs producing E.coli and Kneumoniae was 64.8% and 41.3%,resectively.Pseudomonas aeruginosa kept over 70% drug-susceptibility to Carbapenems.Acinetobacter baumannii just kept drug-susceptibility to major antibiotics over 50%.Conclusion In a word,it was very severe and common about bateria resistant situation in our hospital,which was show enough attention in medical units and administrative department.
出处
《吉林医学》
CAS
2011年第9期1667-1668,共2页
Jilin Medical Journal
关键词
黄石市中医院
2010年
细菌耐药
分析
Huangshi hospital of Chinese Medicine
2010
Drug-resistance
Surveillance analysis