摘要
目的:观察急性根尖周炎常规开髓引流后进行负压引流以减轻临床症状的疗效。方法:将本院收治的急性根尖周炎的患者142例,随机分为实验组(72颗患牙,负压吸引引流)和对照组(70颗患牙,常规开髓引流)。比较两组患者临床症状的缓解情况以及根管内白细胞介素1β(IL-1β)、前列腺素E2(PGE2)及C反应蛋白(CRP)水平的变化。结果:两组数字化疼痛评判法(VAS)差值比较差异具有统计学意义(P<0.05)。实验组IL-1β、PGE2和CRP变化的差值大于对照组(P<0.05),实验组的治疗有效率高于对照组(P<0.05)。结论:应用负压引流等一系列处置能有效缓解急性根尖周炎的症状,愈后良好。
Objective To observe the incidence of pain after treatment of acute periapical periodontitis using negative pressure following opening drainage.Methods 142 patients with acute periapical periodontitis were randomly divided into experimental group（72 teeth） and control group（70 teeth）.The patients in experimental group were treated with negative pressure drainage;the patients in control group were treated with conventional opening drainage.The incidence and degree of pain after root canal preparation and the changes of IL-1β,PGE2 and CRP levels in two groups were recorded.Results There was significant difference of VAS difference value between two groups（P〈0.05）.The changes of IL-1β,PGE2 and CRP levels in experimental group were larger than those in control group（P〈0.05）.The effective rate of treatment in experimental group was higher than that in control group（P〈0.05）.Conclusion The negative pressure drainage can effectively prevent and reduce the pain during root canal therapy of acute periapical periodontitis.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2011年第2期331-334,共4页
Journal of Jilin University：Medicine Edition
基金
吉林省科技厅科研基金资助课题(200705349)
关键词
急性根尖周炎
负压吸引
白细胞介素1Β
前列腺素E2
C反应蛋白
acute periapical periodontitis； negative pressure drainage； interleukin-1； prostaglandinum E2； C-reactive protein；
