摘要
基于扑热息痛还原铬(Ⅵ)和铬(Ⅲ)催化鲁米诺-过氧化氢的化学发光,建立了氧化还原偶合反应流动注射化学发光法测定扑热息痛的新方法。方法线性范围为4.0×10-9～4.0×10-5mol/L,检出限为1.0×10-9mol/L。对4.0×10-7mol/L扑热息痛平行测定8次,其标准偏差为2.7%。已将该方法用于片剂中扑热息痛含量测定。
As chromium（Ⅵ） can be reduced by paracetamol to chromium（Ⅲ） which enhance the CL intensity of luminol-H2O2 system,a new chemiluminescent method for the determination of paracetamol was developed.The relative CL intensity was 1inearly related to the concentration of paracetamol in the range of 4.0×10-9～4.0×10-5mol/L with a detection limit of 1.0×10-9 mol/L.The relative standard deviation（n=8） for 4.0×10-7 mol/L paracetamol was 2.7%.The method has been applied to the determination of paracetamol in the tablets.
出处
《分析试验室》
CAS
CSCD
北大核心
2011年第4期120-122,共3页
Chinese Journal of Analysis Laboratory
基金
商洛学院项目(10SKY015)资助
关键词
流动注射
化学发光
鲁米诺
过氧化氢
扑热息痛
Flow injection
Chemiluminescence
Luminol
Hydrogen peroxide
Paracetamol
