摘要
目的比较静脉输注右美托咪定和靶控输注丙泊酚在内镜逆行性胰胆管造影(ERCP)中的作用。方法 30例ERCP患者随机分为两组:P组靶控输注(TCI)丙泊酚,D组恒速输注右美托咪定。记录不同时点的Richmond躁动镇静量表(RASS)评分,监测生命体征,并统计术中体动发生率和舒芬太尼用量。结果 D组用药后15min、ERCP期间RASS评分均明显高于P组(P<0.05);入恢复室即刻、入恢复室后15min的RASS评分均明显低于P组(P<0.05);但D组ERCP术中体动发生率、舒芬太尼用量均高于P组,且MAP下降、HR减慢较P组明显(P<0.05)。结论右美托咪定用于ERCP的麻醉效果与丙泊酚不等同,且血流动力学更不稳定。
Objective To examine anesthetic effect of dexmedetomidine infusion/targetcontrolled infusion with propofol during eneoscopic retrograde cholangio-panereatography（ERCP）. Methods Thirty patients were randomized enrolled into group D（received dexmedetomidine infusion） and group P[received target-controlled infusion （TCI） propofol]. The Richmond Alertness-Sedation Scale（RASS） and the vital signs were monitored at different time points. Body movement and amount of sufentanil were recorded during ERCP. Result There were higher RASS soere at 15 min post- administration, during ERCP in group D than in group P, immediately been to the postanethesia care unit（PACU） and 15 min post PACU, there were lower RASS socre in group D than in group P （P〈0. 05）,there were high incidence of body movement, great amount of sufemanil and significant decreases on MAP and HR appeared in group D（P〈0. 05）. Conclusion dexmedetomidine is not as effective as propofol for ERCP, and has more instahle hemodynemies.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2011年第3期272-274,共3页
Journal of Clinical Anesthesiology
关键词
右美托咪定
内镜逆行性胰胆管造影
丙泊酚
Dexmedetomidine
Endoscopic retrograde cholangiopanereatography
Propofol
