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视网膜电图明视负向反应研究进展 被引量:1

Advanced progress of the electroretinogram photopie negative response
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摘要 视网膜电图(ERG)的明视负向反应(PhNR)是在明适应条件下用亮光刺激时在正向b波后记录到的一负向电位。灵长类动物实验研究及临床研究证实,PhNR的产生与视网膜神经节细胞(RGCs)及其轴突有关,而研究啮齿类动物发现,PhNR起源于无长突细胞的电活动。就灵长类动物PhNR记录条件的改进、不同记录条件下其波形特点、啮齿类动物PhNR的记录条件及特点,以及局部视网膜PhNR在临床应用中的新进展进行综述。 The photopic negative response (PhNR) from photopic elcctroretinogram (ERG) is a slowly negative potential following positive b wave. The experimental study of primates and clinical observation of patients determined that PhNR arise from retinal ganglion cells (RGCs) and their axons. But the research result of rodents suggested that PhNR of mice and rats, unlike in human and primates, originate from amacrine cells. Recently, the study progress in PhNR is concerned by more and more researchers. The study of PhNR in the focal ERG, the influence of different recording conditions on PhNR wave and the character as well as recording condition of PhNR wave in rodents were introduced in this paper.
出处 《中华实验眼科杂志》 CAS CSCD 北大核心 2011年第3期276-279,共4页 Chinese Journal Of Experimental Ophthalmology
关键词 视网膜电图 明视负向反应 记录方法 啮齿类动物 局部视网膜 Electroretinogram Photopic negative response Recording condition Rodent Focal retina
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