Significance of humoral neopterin in clinical diagnostics and prognosis
Significance of humoral neopterin in clinical diagnostics and prognosis
摘要
Neopterin is bioactive substance released by the activated monocyte/macrophage, and an early and sensitive marker used for reflection of cellular immune activation status induced by the lymphocyte macrophage system. Observation of neopterin levels is conducive to the diagnosis and prognosis of various diseases. This article reviews the existing evidence that neopterin has an important role in cardiovascular risk, infectious diseases, malignancy, autoimmune diseases and transplantaiton.
Neopterin 是激活的单核白血球 / 巨噬细胞释放的 bioactive 物质，并且一个早、敏感的标记为淋巴细胞巨噬细胞系统导致的细胞的有免疫力的激活地位的思考使用。neopterin 层次的观察对各种各样的疾病的诊断和预后导致。这篇文章考察 neopterin 在心血管的风险，传染疾病，恶意，自体免疫的疾病和 transplantaiton 有一个重要角色的存在证据。
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