摘要
目的:总结颞叶神经节细胞胶质瘤的临床及影像表现,重点分析其与癫痫发作的相关性。方法:回顾性分析31例经手术病理证实的累及颞叶的神经节细胞胶质瘤的CT及MRI表现,对肿瘤发生部位、颞叶前部白质异常与癫痫发作相关性进行卡方检验,P<0.05认为差异有统计学意义。结果:31例肿瘤中,囊性病变2例,实性病变12例,囊实性病变17例,仅6例呈典型大囊小结节改变;瘤周轻度水肿13例,中重度水肿6例,未见明显水肿12例;25例肿瘤MRI平扫实性部分以等、长T1,等、长T2信号为主(n=22),信号多不均匀(n=14),囊性部分呈长T1,长T2信号(n=15),信号均匀。24例肿瘤增强示中-重度不均匀强化16例,未见明显强化4例,轻度强化4例。12例肿瘤CT平扫示钙化6例。肿瘤累及海马或海马旁回在癫痫组及非癫痫组的差异有统计学意义(P<0.05)。结论:颞叶节细胞胶质瘤影像表现以实性、囊实性为主,MRI信号及强化多不均匀,水肿较轻,CT可见钙化;患者临床发生癫痫症状与肿瘤累及海马或海马旁回有关。
Objective：To study the clinical and imaging features of temporal ganglioglioma,especially its relationship with epilepsy.Methods：The imaging findings of 31 pathologically confirmed temporal ganglioglioma cases were retrospectively reviewed.Chi-square test was used to analyze the relationship between epilepsy and tumor location and white matter abnormalities,while the statistical significance was set at P0.005.Results：In all of the 31 cases,2 cases showed cystic change,12 cases showed solid change,17 cases showed cystic-solid change,typical large cyst with small nodule was only seen in 6 cases.13 cases showed light edema,6 cases showed moderate-obvious edema,12 cases showed no edema.In 25 cases with MRI scan,the soild part of most cases（n=14） showed iso-low signal on T1WI,iso-high signal on T2WI,the signal was heterogenous in 14 cases,the cystic part usually showed homogenous low signal on T1WI,high signal on T2WI（n=15）.In 24 cases with enhanced scan,16 cases showed moderate-obvious enhancement,4 cases showed mild enhancement,4 cases showed no enhancement.In 12 cases with CT plain scan,calcification was seen in 6 cases.Statistically significant difference was found in hippocampus or parahippocampal gyrus involvement between epilepsy group and non-epilepsy group（P0.05）.Conclusion：Temporal ganglioglioma often shows solid or solid-cystic change,heterogeneous signal on MRI with light edema and heterogeneous enhancement.Calcification can be seen on CT scan.Epilepsy in patients with ganglioglioma is related to hippocampus or parahippocampal gyrus involvement.
出处
《放射学实践》
北大核心
2011年第2期139-142,共4页
Radiologic Practice
