摘要
目的：探讨自发性腹膜炎腹水粒细胞集落刺激因子（Ｇ－ＣＳＦ）测定的临床意义。方法：应用酶联免疫技术测定２５ 例自发性腹膜炎和２５ 例非细菌感染性腹水患者腹水中的Ｇ－ＣＳＦ。结果：在自发性腹膜炎患者腹水中Ｇ－ＣＳＦ阳性率（９２％ ）明显高于非细菌感染性腹水中的阳性率（４％ ），其差异有显著统计学意义（Ｐ＜ ０．００１）。其敏感性为９２％ ，特异性为９６％ 。并且腹水中的Ｇ－ＣＳＦ水平明显高于血清中的水平。随着自发性腹膜炎感染的控制，腹水Ｇ－ＣＳＦ水平逐渐降至正常。结论：腹水Ｇ－ＣＳＦ检测可有效区别自发性腹膜炎与非感染性腹水。
Objective: We studied the clinical significance of measurement of granulocyte colony stimulating factor (G CSF) in ascites of spontaneous bacterial peritonitis (SBP) cases. Methods: G CSF in ascites patients of 25 with SBP and 25 non bacterial infective ascites patients was measured with enzyme linked immunosorbent assay. Results: The positive rate of G CSF in SBP ascites (92%) was much higher than that in non bacterial infective ascites (4%) (P<0.001). Sensitivity and specificity of the measurements were 92% and 96% respectively. G CSF in ascites was higher than that in serum. With the controll of SBP, the level of G CSF decreased to normal. Conclusion: Measurement of G CSF in ascites may be a useful method for differentiating SBP from non bacterial infective ascites. It is also helpful for physician to diagnose SBP earlier by and to observe treatment effects.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
1999年第5期360-361,共2页
Journal of China Medical University
关键词
自发性
腹膜炎
腹水
粒细胞
集落刺激因子
G-CSF
spontaneous bacterial peritonitis
ascites
granulocyte colony stimulating factor
