摘要
为了解玉米芯中水不溶性木聚糖在医药中的应用,采用搅拌下水浸24 h、1.5%次氯酸钠除杂、氢氧化钠碱提、乙酸中和、甲醇醇沉、甲醇及异丙醇醇洗多步法提取了玉米芯中水不溶性木聚糖。研究了所提水不溶性木聚糖的红外光谱及其粒径分布、堆积密度、振实密度、压缩指数、致密性、安息角、流变学等特性。结果表明,红外光谱可用来表征其形态结构。玉米芯中的水不溶性木聚糖密度低、凝聚流动性高,可以作为一种潜在的施药剂。
In order to evaluate xylan as a promise raw material for the pharmaceutical industry,the water-insoluble xylan samples were extracted from corn cobs following several steps：corn cobs was dipersed in water under stirring for 24 h,treated with 1.5% sodium hypochloride,extracted with sodium hydroxide,neutralized with acetic acid and settled down by methanol,washed with methanol and isopropanol.The obtained powder sample was analyzed by infrared spectroscopy.In addition,characterization regarding their particle size distribution,bulk and tap densities,compressibility index,compactability,repose angle and rheological data were also studied.The results demonstrated that infrared spectroscopy were shown to be able to evaluate the xylan structural conformation.Furthermore,xylan powder obtained from corn cobs was characterized as a material with low density and very cohesive flow properties and could be used as a promising polymer for drug delivery.
出处
《化学与生物工程》
CAS
2011年第3期60-62,共3页
Chemistry & Bioengineering
