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中西医结合治疗慢性乙型重型肝炎近期疗效评价方法探讨 被引量:1

Investigation of evaluation methodology for the short-term efficacy of chronic severe hepatitis B treated by TCM combined with western medicine
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摘要 目的通过Meld-Na评分观察中西医结合治疗慢性乙型重型肝炎疗效。方法将49例慢性乙型重型肝炎患者随机分为观察组33例及对照组16例,分别采用中西医结合疗法及和单纯西医疗法治疗。治疗前及治疗后第4周、第8周比较两组Meld-Na评分,评价短期疗效。结果不同预后患者入院时Meld-Na评分有显著差异(P<0.05);观察组有效率明显高于对照组,P<0.05;治疗后4周及8周时Meld-Na评分比较显示,治疗组与对照组有显著差异(P<0.05)。结论 Meld-Na评分能较好预测慢性乙型重型肝炎患者的短期预后,中西医结合治疗对患者Meld-Na评分改善作用明显,能够有效提高短期疗效。 ObjectiveTo observe the efficacy of chronic severe hepatitis B treated by TCM combined with western medicine via the Meld-Na score.MethodsFory-nine patients with chronic severe hepatitis B were divided into observed group(n=33) and control group(n=16),which were treated with combination of TCM with western medicine and western medicine only.The Meld-Na scores before the treatment and 4,8 weeks after treatment were observed respectively,and the short-term effect were evaluated.ResultsPatients with different prognosis had significantly different Meld-Na scores(P0.05);the effective rate of the observed group was significantly higher than that of the control group(P0.05);Meld-Na scores of the 2 groups showed significant difference(P0.05).ConclusionsMeld-Na score can finely predict short-term prognosis of patients with chronic severe hepatitis B,combination of TCM with western medicine can improve patients' Meld-Na score significantly,alsocan improve short-term efficiency.
出处 《山东医药》 CAS 北大核心 2011年第7期25-26,共2页 Shandong Medical Journal
基金 国家科技重大专项"十一五"课题资助项目(2008ZX1005-007)
关键词 肝炎 乙型 慢性 重型 Meld-Na评分 中西医结合 chronic severe hepatitis B Meld-Na score combination of TCM with western medicine
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