摘要
目的探讨慢性阻塞性疾病(COPD)急性发作期的病毒性感染的关系及在其发病机制中的应用。方法选择笔者所在医院自2009年10月～2010年11月收集的41例COPD的急性发作期患者为治疗组(A组),选择36例稳定期患者为观察组(B组),32例正常者作为对照组(C组),采用间接的酶联免疫吸附实验(ELISA)对三组患者的血清进行呼吸道合胞病毒(RSV)、单纯疱疹病毒I型(HSV-I)、副流感病毒(PIV)、腺病毒(ADV)、肺炎衣原体(CP)的特异性抗体IgM、IgG进行检测。结果治疗组的IgM抗体阳性率高于观察组及对照组,三组间比较差异有统计学意义(P<0.01);三组患者的IgG抗体的阳性率比较,治疗组与观察组间比较无统计学差异(P>0.05),治疗组与对照组比较差异有统计学意义(P<0.01)。结论对引发慢性阻塞性肺疾病急性发作的病因进行充分的认识,细菌性病毒感染是COPD急性发作的期的重要的诱因,与COPD的发病具有相关性。
Objective To investigate the effect of viral infections of the respiratory tract on the acute exacerbation of chronic obstructive pulmonary disease.Methods Our hospital from October 2009 to November 2010 collected 41 cases of acute exacerbation of COPD patients for the treatment group,36 patients with stable patients in the observation group,32 normal patients as control group.ELASA were used to detect the IgM and IgG of RSV,HSV-I,PIV,ADV and CP.Results The treatment group and observation group and control group were RSV,HSV-I,PIV,ADV,CP of IgM antibodies were positive,differences between the three group was significant（P0.01）.Conculsion On the cause of chronic obstructive pulmonary disease with acute onset of a full understanding of the etiology of the virus infection is the period of acute COPD important incentive,while the incidence of HIV infection and COPD is relevant.
出处
《中外医学研究》
2011年第9期9-10,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
慢性阻塞性肺疾病
急性发作
病毒感染
呼吸道病毒
Chronic obstructive pulmonary disease
Acute
Virus infection
Respiratory virus
