摘要
目的研究阿奇霉素治疗小儿支气管肺炎的临床疗效。方法黄河三门峡医院采用注射用乳糖酸阿奇霉素治疗小儿支气管肺炎60例。阿奇霉素剂量按10mg/（kg.d）,用0.9%氯化钠注射液或5%葡萄糖注射液配制成阿奇霉素浓度为1.0 mg/ml静脉滴注1~3h,疗程为5~7d。观察治疗前后症状、体征变化及外周血、肝功能、肾功能、X线胸片变化,并取咽部或上呼吸道分泌物做细菌培养及阿奇霉素药敏试验,或取上呼吸道分泌物及血清进行支原体等非典型病原菌抗原或抗体检测。结果痊愈26例,显效30例,好转4例,总有效率为93.3%。10例发生不良反应,占16.7%,其中纳差5例,恶心、腹痛3例,皮肤风团1例,静脉滴人处疼痛1例,停药1天后不良反应消失。结论乳糖酸阿奇霉紊治疗小儿支气管肺炎临床疗效好,安全性较高。
Objective To study the clinical efficacy of treatment of children with bronchial pneumonia azithromycin.Methods Lactose azithromycin injection for treatment of children with bronchial pneumonia 60 cases.Azithromycin dose by 10mg/（kg·d）,with 0.9% sodium chloride injection or 5% glucose injection preparation of azithromycin concentration of 1.0 mg / ml intravenous infusion of 1 ~ 3h,duration of treatment was 5 ~ 7d.Before and after treatment the symptoms,physical signs,peripheral blood and liver function,kidney function,X-ray changes,and to take throat or upper respiratory secretions for bacterial culture and susceptibility testing of azithromycin,or take on the respiratory secretions and serum and other atypical pathogens Mycoplasma antigen or antibody detection.Results 26 patients cured,effective 30 cases,4 cases improved,with a total effective rate was 93.3%.Adverse reactions occurred in 10 cases,accounting for 16.7%,of which 5 cases of anorexia,nausea,abdominal pain in 3 cases,one case of skin,the wind group,pain at intravenous drip were 1 case of adverse reaction disappeared after 1 day withdrawal.Conclusion Azithromycin lactobionate for treatment of children with bronchial pneumonia mycophenolate has good clinical efficacy,and safety is high.
出处
《医药论坛杂志》
2010年第22期104-105,共2页
Journal of Medical Forum
关键词
乳糖酸
阿奇霉素
儿童
支气管肺炎
Lactose acid
Azithromycin
Children
Bronchial pneumonia
