摘要
目的探讨贵阳市重症手足口病的发病流行特点,为有效预防与控制重症手足口病提供科学依据。方法由贵阳市疾病预防控制中心疾控人员使用统一调查表格,对2009年贵阳市报告的全部重症病例进行个案调查和采集样本。采用RT-PCR法检测患者样本的肠道病毒71型（EV71）、柯萨奇病毒A组16型（CoxA16）及其他肠道病毒。结果 2009年全市共报告手足口病6 397例,2009年手足口病病例报告数较2008年上升145.75%,其中重症手足口病220例,重症率为3.44%;手足口病死亡12例,病死率为0.19%,重症患者的死亡比为5.45%。男女性的重症率差异无统计学意义（χ2=1.62,P〉0.05）;重症病例主要集中时间为7~10月,以散居儿童为主（70.00%）;临床表现以发热和出疹为主;重症患者EV71的检出率为16.30%,CoxA 16的检出率为0.54%,其他肠道病毒为26.63%。结论 2009年我市重症手足口病主要发生在3岁以下儿童,夏秋季节多发,应加强在流行季节的防控工作及3岁以下手足口病患儿的病情监测与治疗,减少重症手足口病例和死亡病例的发生。
Objectives】 To find out the prevalence of severe hand-foot-mouth disease cases in 2009 of Guiyang,and provide the scientific basis for the effective prevention and control of severe HFMD.【Methods】 CDC staff,use the unified survey form,investigation and collection of samples all cases of severe disease case in 2009,Guiyang.Using RT-PCR method to detect samples of patients with enterovirus 71（EV71）,Coxsackie virus A group of 16 （CoxA 16） and other enteroviruses.【Results】 A total of 6 397 cases of HFMD were reported in 2009,Guiyang.The number of HFMD cases increased over 2008 by 145.75%,severe HFMD have 220 cases and the severe rate is 3.44%,HFMD patients died 12,mortality was 0.19%.Severe HFMD mortality was 5.45%.males and females were no significant differences in the severe rate（χ2=1.62,P〈0.05）;Severe HFMD cases focused on July-October,chil-dren mainly to scattered children（70.00%）,clinical manifestations mainly fever and rash;In all severe HFMD,the detection rate of EV71 cases was 16.30%,the detection rate of CoxA16 was 0.54%,other Enterovirus was 26.08%;【Conclusion】 In 2009,severe HFMD children of Guiyang occurs mainly in under 3 years old,mainly occurred in the summer and autumn.In popular season,we should be not only strengthened prevention and control under 3 years old,but monitoring and treating HFMD,reduce severe HFMD case and death cases.
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2010年第24期3826-3829,共4页
China Journal of Modern Medicine
关键词
重症手足口病
流行分析
贵阳市
severe Hand-foot-mouth disease
epidemiological analysis
Guiyang city
