摘要
目的观察抗癌方联合肝动脉化疗栓塞术(TACE)治疗气虚血瘀型原发性肝癌(HCC)对中医证候、甲胎蛋白以及CT复查肿瘤的改善情况,以探讨联合治疗对该病的近期疗效、生存质量及生存率的影响。方法采用前瞻性对照研究,选择64例原发性肝癌(气虚血瘀型)患者,随机分为2组,每组32例,治疗组:TACE治疗基础上口服抗癌方煎剂,对照组:单纯行TACE治疗。结果治疗组与对照组总有效率分别为90.6%(29/32)、65.6%(21/32),肿瘤初次复发率分别为9.37%(3/32)、34.38%(11/32),两组比较差异有统计学意义(P<0.05);联合治疗能有效降低血清甲胎蛋白水平,显著改善中医证候,与对照组比较差异有统计学意义(P<0.05)。结论抗癌方联合TACE治疗气虚血瘀型HCC患者,可以明显改善患者的生存质量、减少肿瘤的复发并提高患者的生存率。
Objective To observe the effect of Anticancer decoction combined with TACE for HCC in Qi-deficiency and blood stasis on improving syndrome,AFP and CT result for investigation of ETR,life quality and survival rate.Methods 64 patients with HCC in Qi-deficiency and blood stasis were divided randomly into two groups,32 in each group.The patients in therapeutic groups treated with Anti-cancer decoction combined with TACE and in control group with TACE only.Results The total effective rates in both groups were 90.6%（29/32） and 65.63%（21/32）;the initial tumor recurrence rates were 9.37%（3/32） and 34.38%（11/32）;and the combined treatment to reduce serum level of alpha-fetoprotein in improving TCM syndrome was better than TACE only was（P〈0.05）.Conclusion The combined treatment is effective for HCC in Qi-deficiency and blood stasis,which can improve significantly the survival quality of the patients,reduce reoccurring of the cancer and increase the survival rate of the patients.
出处
《湖南中医药大学学报》
CAS
2010年第11期55-57,共3页
Journal of Hunan University of Chinese Medicine
基金
2007年度深圳市科技局资助项目(200702133)
关键词
原发性肝癌
抗癌方
肝动脉化疗栓塞术
黄芪
白术
莪术
临床研究
hepatocellular carcinoma（HCC）
anti-cancer decoction
TACE
Radix astragal
white atractylodes rhizome
curcuma zedoary
clinical curative effect
