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左旋门冬酰胺酶治疗急性淋巴细胞白血病不良反应 被引量:14

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摘要 目的观察左旋门冬酰胺酶(L-ASP)在治疗急性淋巴细胞白血病(ALL)过程中的不良反应。方法回顾分析15例应用L-ASP疗程及不应用L-ASP的疗程不良反应比较,并观察治疗后不良反应改善情况。结果应用L-ASP疗程可出现凝血障碍、低蛋白血症,其他毒副作用如骨髓抑制、胃肠反应、黄疸、肝酶升高、焦虑高于未应用L-ASP疗程。结论积极预防可减少L-ASP的不良反应,保证化疗顺利进行,及时诊断和处理L-ASP的不良反应可减少严重合并症的发生,提高急性淋巴细胞白血病患者的无病生存率。
出处 《安徽医药》 CAS 2011年第3期365-366,共2页 Anhui Medical and Pharmaceutical Journal
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