期刊文献+

fMRI技术在胆碱能药物及其他神经递质药物研究中的作用及其在中医药疗效评价中的应用展望 被引量:4

Application of functional MRI on evaluation of cholinergic drugs and other neurotransmitter drugs and its prospect in traditional Chinese medicine evaluation
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摘要 胆碱能药物是常被用于神经疾病的一类神经递质类药物,其药效评估研究中fMRI已经得到了广泛的应用。文章以胆碱能药物为例,系统归纳和总结了使用功能磁共振技术对胆碱能药物在与认知相关的记忆、注意、情绪、视觉研究方面的评价作用,并结合中医药的自身规律和用药特点,对其在未来中医药疗效评价,尤其是脑病治疗相关药物以及与情志调节相关药物的疗效评价中的重要意义。作者综述了近年来功能磁共振技术在神经药理学研究方面的工作进展。 This article summarizes the progress of the application of functional magnetic resonance image(fMRl) on neurophar- macology. Cholinergic drugs are types of neurotransmittemrswhich are usually used to treat neurological disorders, fMRI is widely used in the research of evaluation of cholinergic drugs. This article systematically summerizes the research of drug evaluation on memory, attention, emotion and vision by fMRI using the cholinergic drugs for example. Combined with the charactors and disciplines of traditional Chinese medicine ( TCM), this article also makes a prospect of the application of fMRI on traditional Chinese medicine evaluation, especially the drugs on brain disease and emotional modulation.
出处 《中国中药杂志》 CAS CSCD 北大核心 2011年第6期810-813,共4页 China Journal of Chinese Materia Medica
基金 国家自然科学基金重点项目(30930031) 国家自然科学基金项目(30873458) 北京市自然科学基金项目(7082050) 全国优秀博士论文专项基金项目(2007B7) 高等学校博士学科点基金项目(200800271014) 北京师范大学自主科研基金重点项目(248-105102)
关键词 功能磁共振(fMRI) 胆碱能药物 中医药 疗效评价 functional magnetic resonance image(fMRl) cholinergic drug traditional Chinese medicine (TCM) drug evaluation
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