摘要
目的利用3.0 T MR扩散加权成像(DWI)测量肝硬化患者及健康自愿者肝脏表观扩散系数(ADC)值,探讨ADC阈值在诊断肝硬化严重程度中的价值。资料与方法 (1)肝硬化组:肝硬化患者53例,男35例,女18例,年龄30～76岁,平均(55.02±12.56)岁,Child-Pugh A、B、C级患者分别为18例、25例和10例。(2)对照组:健康自愿者30名,其中男18名,女12名,年龄30～79岁,平均(52.34±12.68)岁。两组均采用3.0T磁共振扫描仪行DWI,分别测量3组b值(500、800和1000s/mm2)下肝脏的ADC值。结果 b=500和1000s/mm2时诊断肝硬化的敏感性和特异性均较b=800s/mm2高;同时b=500s/mm2诊断肝硬化的敏感性和特异性又较b=1000s/mm2高。结论 MR-DWI ADC阈值在评价肝硬化严重程度上具有很高的敏感性和特异性。
Objective To evaluate the role of threshold DWI ADC value in diagnosis of the severity of hepatic liver cirrhosis by measuring the ADC values of the liver in both hepatic cirrhosis patients and normal healthy volunteers by 3.0 Tesla MR DWI.Materials and Methods （1）Hepatic cirrhosis group：53 hepatic cirrhosis patients,included 35 males and 18 females,mean age of （55.02±12.56） years,range from 30 to 76 years.The number of Child-Pugh class A,B,C patients were 18,25,and 10 cases,respectively.（2）Control group：30 normal healthy volunteers,included 18 males and 12 females,with mean age of 55.34±12.68 years,range,from 30 to 79 years.Two groups underwent DWI examination by 3.0 T MRI,the ADC value of liver were measured under 3 groups of b values （500,800 and 1000 s/mm2）.Results With the b value of 500 s/mm^2 and 1000 s/mm^2 to diagnose hepatic cirrhosis of the liver,the sensitivity and specificity were higher than that with 800 s/mm2,meantime,when using 500 s/mm^2,the sensitivity and specificity were higher than that with 1000 s/mm^2.Conclusion The threshold ADC value has a great role in the evaluation of the severity of hepatic cirrhosis.
出处
《临床放射学杂志》
CSCD
北大核心
2011年第2期206-209,共4页
Journal of Clinical Radiology
关键词
肝硬化
CHILD-PUGH分级
扩散加权成像
表观扩散系数
Hepatic cirrhosis Child-Pugh classification Diffusion weighted imaging Apparent diffusion coefficient
