摘要
目的观察斑蝥酸钠维生素B6注射液辅助肺癌术后化疗的临床疗效及对化疗毒副反应的影响。方法将64例肺癌术后患者随机分为2组,治疗组32例在常规化疗及对症处理基础上应用斑蝥酸钠维生素B6注射液;对照组32例予常规化疗及对症处理。2组均治疗2周后观察疗效和化疗毒副反应的发生情况。结果治疗组有效率59.4%,对照组34.4%,2组有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。2组化疗毒副反应发生率比较差异有统计学意义(P<0.05),治疗组低于对照组。结论斑蝥酸钠维生素B6注射液具有增强化疗疗效、改善患者症状、减少化疗毒副反应的作用。
Objective To investigate the effect of combination of disodium cantharidinate and vitamin B6 injection adjuvant chemotherapy on patients with lung cancer postoperation.Methods 64 patients with lung cancer postoperation were randomly divided into two groups.Patients in control group（n=32） received routine chemotherapy.32 cases in treatment group received combination of disodium cantharidinate and vitamin B6 injection adjuvant chemotherapy.The therapeutic effect and toxic and side effect were observed after treatment of two weeks.Results The effective rate in treatment group was superior to that in control group（P0.05）.Toxic and side effect in treatment group was less than that in control group（P0.05）.Conclusion Combination of disodium cantharidinate and vitamin B6 injection can reinforce effect of chemotherapy,improve symptoms of patients,and decrease toxic and side effect of chemotherapy.
出处
《河北中医》
2011年第1期92-93,共2页
Hebei Journal of Traditional Chinese Medicine
