摘要
目的:了解牛磺酸滴眼液的渗透压现状及处方组成对其影响情况。方法:采用SMC-30B渗透压摩尔浓度测定仪,采用冰点下降法对国内5个厂家牛磺酸滴眼液进行渗透压摩尔浓度测定。结果:多数牛磺酸滴眼液的渗透压均高出人眼可耐受的渗透压范围,处方组成的不合理是造成渗透压超标的主要因素。结论:牛磺酸滴眼液的渗透压现状亟待解决,其处方组成需要进一步研究改进。
Objective：In order to understand the current information about the osmotic pressure of taurine eye drops and the influence of components of the formulation.Method：Using SMC-30B osmotic pressure tester to measure the osmolality of taurine eye drops of the 5 factories by freezing-point depression method.Results：Most of the samples have higher osmotic pressure beyond the tolerance of human＇s eyes,the unreasonable prescription is the main factor leading to the results.Conclusion：The situation of Taurine eye drops of osmotic pressure is urgently to be solved.Component of formulation needs to be further studied and improved.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2011年第3期589-591,共3页
Chinese Journal of Pharmaceutical Analysis
