摘要
目的掌握浙江省人间布鲁氏菌病(布病)流行规律及分布状况,为今后制定防治策略提供参考依据。方法采用虎红平板凝集试验和试管凝集试验对全省涉及牛、羊畜交易、屠宰、养殖、挤乳、畜产品加工、海洋动物加工及兽医等重点职业人群进行血清学检测。结果全省12个地市2005-2009年共监测重点人群26980人,检出血清学阳性者535例,阳性率为2.0%,其中确诊新发病例143例,新感染者392例,监测点由2005年涉及50个县(区)增加到2009年的59个;绍兴市和金华市分别为检出病例及感染者数最高地区,分别占总病例数的41.3%(59/143)和总感染者数的40.8%(160/392);随着年份的增加,亚急性、慢性布病病例所占比例逐年下降(2χ趋势=10.04,P=0.002);主动检出病例数所占比例呈逐年增加趋势(2χ趋势=3.93,P=0.048)。结论近5年来,新的布病疫点不断出现,确诊的患者数及感染者人数呈逐年上升趋势,而且上升的速度很快。与多部门密切配合,加强牲畜流通环节的检疫和管理,做好重点羊交易市场人群布病的主动监测、健康教育等工作是今后布病防治工作的重点。
Objective To analyze the epidemiological characteristics of human brucellosis in Zhejiang and provide scientific evidence for the development of the preventive and control measures. Methods By using Rose Bengal plate agglutination test （RBPT） and standard tube agglutination test （ SAT ）, serological detection was conducted in risk populations with occupational exposure to Brucella, including livestock traders, slaughters, raisers, milkmaids, veterinary and people engaged in livestock or sea products processing, in Zhejiang. Results From 2005 to 2009, 26 980 persons in 12 municipalities （prefecture） received the detection, 535 were serological positive （2. 0% ）, of which 143 were diagnosed as brucellosis and 392 were bacteria carriers. The number of surveillance sites increased from 50 in 2005. to 59 in 2009. The detection rate of brucellosis cases in Shaoxing and the detection rate of carriers in Jinhua were highest, accounting for 41.3 % （59/143） and 40. 8 % （160/392） of the totals respectively. The proportion of sub acute 2 and chronic cases declined by years （X^2trend = 10. 04, P = 0. 002 ） , but the proportion of the cases detected actively 2 increased by years （X^2trend = 3.93, P = 0. 048）. Conclusion In recent years, new brucellosis epidemic area emerged in Zhejiang, resulting in the rapid increases of newly diagnosed cases and carriers. It is necessary to strengthen the quarantine and management in livestock trading, active surveillance in goat market and health education by close multi sectoral cooperation to prevent and control brucellosis in Zhejiang.
出处
《疾病监测》
CAS
2011年第2期130-132,共3页
Disease Surveillance
