摘要
[目的]探讨急性心肌梗死（AMI）与缺血性脑卒中危险因素的异同.[方法]分析137例AMI患者和132例急性缺血性脑卒中患者的疾病史、家族疾病史、生活方式因素以及入院后血糖、血脂、血纤维蛋白原等生化检测资料.[结果]AMI患者的吸烟率、吸烟〉20支/日比例、高血压家族史、阳性心血管病家族史、既往高脂血症患病率均显著高于缺血性脑卒中患者（P〈0.01）.缺血性脑卒中患者的既往高血压患病率（66.7%）明显高于AMI患者的既往高血压患病率（46.7%）（P〈0.01）.AMI患者的平均高密度脂蛋白胆固醇（HDL-C）水平、总胆固醇水平和低密度脂蛋白胆固醇（LDL-C）水平均显著低于缺血性脑卒中患者（P〈0.01）.AMI患者的平均血纤维蛋白原水平显著高于缺血性脑卒中患者（P〈0.01）.二组平均甘油三酯和空腹血糖水平比较无统计学差异.[结论]吸烟、高血压家族史、阳性心血管病家族史、既往高脂血症史、高纤维蛋白原血症作为发病危险因素与心肌梗死的密切程度大于缺血性脑卒中 高血压与缺血性脑卒中的关系更为密切.发病急性期缺血性脑卒中患者的平均总胆固醇水平和低密度脂蛋白胆固醇水平高于AMI患者.
[Objective] To explore the difference of the risk factors between acute myocardial infarction （AMI） and ischemic stroke. [Methods] Case history, family history, life style and biochemical indicators in admission including blood glucose, blood lipid and plasma fibrinogen in 137 AMI patients and 132 patients with acute ischemic stroke were collected. [Results] The rate of smoking, smoking more than 20 pieces daily, family history of hypertension, family history of cardiovascular disease and history of hyperlipoidemia in AMI patients were significantly higher than those in ischemic stroke patients（ P〈0.01）. Prevalence of hypertension in ischemic stroke patients（66.7%） was significantly higher than that in AMI patients（46.7%）（ P〈0.01）. Mean levels of HDL-C, TC and LDI.-C in AMI patients were significantly lower than those in ischemic stroke patients（ P 〈0.01）. The mean level of plasma fibrinogen in AMI patients was significantly higher than that in ischemie stroke patients（ P 〈0.01）. No significant difference was found in the mean level of TG and fasting glucose between AMI and ischemic stroke. [Conclusion] Smoking, family history of hypertension, family history of cardiovascular disease, history of hyperlipoidemia and high plasma fibrinogen have more close relationship with myocardial infarction than ischemic stroke. History of hypertension has more close relationship with ischemie stroke. In the acute stage, the mean levels of TC and LDLC in ischemic stroke patients are higher than those in AMI patients.
出处
《医学临床研究》
CAS
2011年第2期241-243,共3页
Journal of Clinical Research
