摘要
目的探讨鼻康喷雾剂对小鼠红细胞的免疫调节作用。方法以照射法造模，给予中药鼻康喷雾剂灌胃，应用酵母菌红细胞花环实验法测定小鼠红细胞免疫黏附功能。结果与空白对照组[RBc．C3bRR花环率为（11．1±2．3505），RBC—ICR花环率为（8．7±1．0814）]比较，鼻康喷雾剂大剂量组[RBC—C3bRR花环率（19．7±2．2509），RBC．ICR花环率（5．7±1．7826）]、中剂量组FRBC—C3bRR花环率（17．2±3．2846，RBC．ICR花环率（6．0±1．8326）]，差异均有统计学意义（P均〈0．01），小剂量组[RBc—C3bRR花环牢（12．5±3．8370），RBC．ICR花环率（7．9±2．8191）]差异无统计学意义。结论鼻康喷雾剂可提高小鼠红细胞的免疫功能，具有免疫调节作用。
Objective To study the immunological regulation of Nasal Healing Spraying Agent （NHSA）. Methods Test models were setup by irradiation. The models were administrated with NHSA by lavage and immune adherence of red cells was tested by chaplet experiment with blank and positive control. Results NHSA could increase Red Blood Cell-C3b Receptor Rosette （RBC-C3bRR） and reduce Red Blood Cell-Immune Complex Rosette （RBC-ICR） in mice. Compared with blank control group, the results in the high dose group and middle dose group were statistically significant （P〈0.01）. The result also showed that NHSA could elevate the quantity and activity of Red Blood Cell-C3b Receptor （RBC-CabR） and reduce the Immune Complex （IC） to enhance the red cell immune function in mice effectively. Conclusion NHSA could elevate the RBC immunity function in mice and increase immunoregulatory function.
出处
《国际中医中药杂志》
2011年第3期212-213,共2页
International Journal of Traditional Chinese Medicine
基金
国家自然基金青年科学基金项目（项目编号：30801510）
关键词
鼻康喷雾剂
小鼠红细胞免疫试验法
免疫调节
Nasal Healing Spraying Agent （NHSA）
Test for red blood cellular immunity in mice
Immunoregulatory function
