摘要
本文就脑卒中后疲劳的概念、发病率、诊断、危险因素、发生机制及治疗等方面的研究进展进行综述。脑卒中后疲劳是卒中恢复期独立于抑郁的常见症状,影响患者的康复与生存质量。脑卒中后疲劳的发生机制尚未明确,可能与社会心理及生物学因素均有关。生物学机制包括了梗塞部位或脑部基础病变累及特定的皮层-皮层下环路,以及免疫、神经内分泌及神经递质异常等。目前尚无肯定的有效治疗方法。
The concept, prevalence, risk factors, mechanisms and treatment of PSF were reviewed. Poststroke fatigue （PSF） is a common problem independent of depression in stroke survivors, interferes with rehabilitation and has a negative effect on their quality of life. The machanisms of PSF are uncertain. Both social psychological and biological factors may contribute to the development of PSF. The biological mecha- nisms include the involvement of specific cortieal-subcortical circuits by infarctions and pre-existing cerebral abnonnalitie,as well as immunological, neuroendoerinal and neurotransmitters changes in stroke survivors. Update, no drugs have been proved to be effective in the treatment of PSF.
出处
《中华脑血管病杂志（电子版）》
2011年第1期37-41,共5页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词
脑卒中
疲劳
康复
Stroke
Fatigue
Rehabilitation
