摘要
目的探讨胰岛素泵强化对老年女性早期糖尿病肾病的影响。方法将60例老年女性早期糖尿病肾病患者随机分为两组,每组各30例。观察组使用门冬胰岛素泵进行血糖控制,对照组使用普通胰岛素进行血糖控制,然后比较两组疗效。结果两组治疗前后的尿微量白蛋白排泄率(UAER)和β2微球蛋白(β2-MG)存在显著差异,但观察组比对照组更为明显,P<0.05;在血糖比较上,除凌晨3点,其余各时间段两组血糖均较治疗前有显著下降,P<0.05,但两组治疗前后的内生肌酐清除率(Ccr)却没有显著变化,P>0.05。结论胰岛素泵强化治疗能显著降低患者的尿微量白蛋白和β2微球蛋白,治疗效果比较理想,值得临床推广。
Objective To explore the effect of insulin pump intensive treatment for the elderly female with early diabetic nephropathy. Methods 60cases with DN were rando-mly divided into observation（3casee, was given by insulin pump intensive treatment） grou-p and control group（30cases,was given by treatment of ordinary insulin）,and then compare the two groups’ effect. Results The two groups’UAER and β2-MG had significant differe-nce, but the observation group’s was more obvious ,for the blood sugar, except the am 3：00, all the period had significant change, P0.05; But its Ccr had no significant change, P0.05. Conclusion The treatment of insulin pump intensively could significantly decree-se the patents’UAER and β2-MG,should be promoted.
出处
《当代医学》
2011年第8期106-107,共2页
Contemporary Medicine
