期刊文献+

胃间质瘤经腹腔镜与开腹手术治疗效果的临床对照研究 被引量:5

A randomized controlled trial: Laparoscopic surgery versus open surgery for the treatment of gastric stromal tumor
下载PDF
导出
摘要 目的探讨腹腔镜胃间质瘤切除术较传统开腹手术的治疗效果、安全性。方法28例胃间质瘤患者分别采用经腹腔镜或常规开腹手术行胃间质瘤切除术,主要比较两组的术后并发症、早期复发情况,并以此推测两种术式在手术安全性的优劣。结果手术时间腹腔镜手术组为(100.7±24.8)min,开腹手术组(95.0±22.4)min,差异无统计学意义(P〉0.05);术中失血量腹腔镜手术组为(56.4±18.1)ml,(83.9±27.3)ml,差异有统计学意义(P〈0.05);术后排气时间腹腔镜手术组为(69.4±32.3)h,开腹手术组(104.6±20.7)h,P〈0.05,住院时间腹腔镜手术组(8.8±1.8)d,开腹组为(11.4±1.5)d,P〈0.05;术后并发症腹腔镜组1例,开腹组2例,P〉0.05。随访期内(6~24个月)Kaplan—Meier生存分析差异无统计学意义(P〉0.05)。结论在熟练掌握腹腔镜手术的基础上行胃间质瘤切除术是安全的,且患者创伤小、康复快,治疗效果与开腹手术无差别。 Objective To explore the clinical efficacy of laparoscopic resection of gastric stromal tumor versus open resection, and assess the feasibility and effectiveness of the laparoscopic approach. Methods A total of 28 patients with gastric stromal tumors were divided into 2 groups : laparoscopy group and open resection group. Postoperative complications and recurrence were compared between the two groups. Results There was no significant difference in postoperative complications and recurrence be- tween the two groups. The operation time in the laparoscopy group was ( 100.7 ± 24.8 ) min, similar to that in the open resection group(95.0 ±22.4) min (P 〉 0.05 ). The blood loss in the laparoscopy group was ( 56.4 ± 18.1 ) ml, significantly less than that in the open resection group ( 83.9 ± 27.3 ) ml ( P 〈 0.05 ). The exhaust time after the operation and the length of hospital stay in the laparoscopy group were(69.4 ± 32.3 ) h and ( 8. 8 v 1.8 ) d respectively, significantly shorter than those in the open resection group [ ( 104.6 ± 20.7 ) h and ( 11.4 ± 1.5 ) d ] ( P 〈 0.05 ). Postoperative complications and short - term cumu- lative survival rates of the 2 groups had no significant difference ( P 〈 0. 05 ). Conclusion Laparoscopic resection of gastric stromal tumors can be performed safely and effectively in patients with gastric stromal tumor with the advantage of minimal invasiveness and good clinical efficacy.
出处 《临床外科杂志》 2011年第2期97-100,共4页 Journal of Clinical Surgery
关键词 胃间质瘤 腹腔镜 外科治疗 gastric stromal tumors laparoscopes surgical procedures
  • 相关文献

参考文献18

  • 1Gelen T, Elpek GO, Aksoy NH, et al. p27 labeling index and proliferation in gastrointestinal stromal tumors:correlations with clinicopathologic fac- tors and recurrence[ J]. Jpn J Clin Oncol,2003,33(7) :346-352. 被引量:1
  • 2Crosby JA, Catton CN, Davis A, et al. Malignant gastrointestinal stromal tumors of the small intestine : a review of 50 cases from a prospective da- tabase[ J]. Ann Surg Oncol,2001,8( 1 ) :50-59. 被引量:1
  • 3Miettinen M, Lasota J. Gastrointestinal stromal tumors - definition, clinica, histologica, immunohistochemica, and molecular geneticfeatures and differential diagnosis[J]. Virchows Arch ,2001,438 ( 1 ) : 1-12. 被引量:1
  • 4Fletcher CD, Berman J J, Corless C, et al. Diagnosis of gastrointestinal stromal tumors : a consensus approach [ J ]. Hum Pathol, 2002,33 ( 5 ) : 459 -465. 被引量:1
  • 5DeMatteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stro- mal tumors:recurrence patterns and prognostic factors for survival [ J ]. Ann Surg,2000,231 ( 1 ) :51-58. 被引量:1
  • 6刘念,耿小平.胃肠间质瘤的临床诊疗进展[J].消化外科,2006,5(4):291-294. 被引量:12
  • 7Eisenberg BL, Judson I. Surgery and imatinib in the management of GIST: emerging approaches to adjuvant and neoadjuvant therapy [ J ]. Ann Surg Oncol, 2004,11 ( 5 ) :465 -475. 被引量:1
  • 8Kndblom LG. Gastrointestinal stromal tumors : diagnosis, epidemiology, prognosis [ C ]. ASCO Annual Meeting, Chieago,2003. 被引量:1
  • 9Blanke C, Eisenberg BL, Heinrich M. Epidemiology of GIST[ J]. Am J Gastroentero,2005,100( 10 ) :2366. 被引量:1
  • 10Basso N, Rosato P, De Leo A, et al. Laparoscopic treatment of gastric stromal tumors [ J ]. Surg Endosc ,2000,14 ( 6 ) : 524-526. 被引量:1

二级参考文献28

  • 1Bucher P, Egger JF, Gervaz P, et al. An audit of surgical management of gastrointestinal stromal tumours (GIST). Eur J Surg Oncol, 2006, 32: 310-314. 被引量:1
  • 2DeMatteo RP, Lewis JJ, Leung D, et al. Two hundred gastrointestinal stromal tumors. Ann Surg, 2000, 231:51-58. 被引量:1
  • 3Nguyen SQ, Divino CM, Wang JL, et al. Laparoscopic management of gastrointestinal stromal tumors. Suvg Endosc, 2006, 20: 715-716. 被引量:1
  • 4Hepworth CC, Menzies D, Motson RW. Minimally invasive surgery for posterior gastric stromal tumors. Surg Endosc, 2000, 14 : 349-353. 被引量:1
  • 5Moehizuki Y, Kodera Y, Fujiwara M, et al. Lapareseopic wedge resection for gastrointestinal stromal tumors of the stomach: initial experience. Surg Today, 2006, 36:341-347. 被引量:1
  • 6Brainard JA, Goldblum JR. Stromal tumor of the jejunum and ileum : a clinicopathologic study of 39 cases. Am J Surg Pathol, 1997, 21:407-416. 被引量:1
  • 7Lehnert T.Gastrointestinal sarcoma (GIST)-a review of surgical management[J].Ann Chir Gynaecol,1998,87(4):297-305. 被引量:1
  • 8Rossi C R,Mocellin S,Mencarelli R,et al.Gastrointestinal stromal tumors:from a surgical to a molecular approach[J].Int J Cancer,2003,107(2):171-176. 被引量:1
  • 9Pierie J P,Choudry U,Muzikansky A,et al.The Effect of surgery and grade on outcome of gastrointestinal stromal tumors[J].Arch Surg,2001,136(4):383-389. 被引量:1
  • 10DeMatteo R P,Shah A,Fong Y,et al.Results of hepatic resection for sarcoma metastatic to liver[J].Ann Surg,2001,234(4):540-547. 被引量:1

共引文献14

同被引文献47

  • 1Kong SH, Yang HK. Surgical treatment of gastric gastroin- testinal stromal tumor[J]. J Gastric Cancer, 2013, 13( 1 ) : 3- 18. 被引量:1
  • 2Athanasiou T, A1-Ruzzeh S, Kumar P, et al. Off-pump myocardial revasculari- zation is associated with less inci- dence of stroke in elderly patients[J]. Ann Thorac Surg, 2004, 77(2): 745-753. 被引量:1
  • 3Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample[J]. BMC Med Res Methodol, 2005, 20(5): 13. 被引量:1
  • 4Matthews BD, Walsh RM, Kercher KW, et al. Laparoscop- ic vs open resection of gastric stromal tumors[J]. Surg En- dosc, 2002, 16(5):803-807. 被引量:1
  • 5Ishikawa K, Inomata M, Etoh T, et al. Long-term outcome of laparoscopic wedge resection for gastric submucosal tu- mor compared with open wedge resection[J]. Surg Laparosc Endosc Percutan Tech, 2006, 16(2): 82-85. 被引量:1
  • 6Nishimura J, Nakajima K, Omori T, et al. Surgical strategy for gastric gastrointestinal stromal tumors: laparoscopic vs. open resection[J]. Surg Endosc, 2007, 21(6): 875-878. 被引量:1
  • 7Pitsinis V, Khan AZ, Cranshaw I, et al. Single center ex- perience of laparoscopic vs open resection for gastrointesti- nal stromal tumors of the stomach[J]. Hepatogastroenterology, 2007, 54(74): 606-608. 被引量:1
  • 8Catena F, Di Battista M, Fusaroli P, et al. Laparoscopic treatment of gastric GIST: report of 21 cases and literature's review[J]. J Gastrointest Surg, 2008, 12(3): 561-568. 被引量:1
  • 9Silberhumer GR, Hufschmid M, Wrba F, et al. Surgery for gastrointestinal stromal tumors of the stomach[J]. J Gastroin- test Surg, 2009, 13(7): 1213-1219. 被引量:1
  • 10许东,吴硕东,于宏.胃间质瘤的腹腔镜手术与开腹手术的临床对比研究[J].生物医学工程和临床,2009,13(2):123-125. 被引量:1

引证文献5

二级引证文献15

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部