摘要
目的探讨病理性妊娠患者血清ACA、β-HCG表达水平及其与病理性妊娠发病的相关性。方法 选择在我院门诊行产前检查的孕妇122例,其中病理性妊娠组82例和正常妊娠组40例。采用酶联免疫法(ELISA)检测两组血清ACA的含量以及电化学发光免疫法(ECLIA)检测β-HCG的含量。结果病理性妊娠组孕妇血清ACA和β-HCG水平均明显高于正常妊娠组(P<0.05);病理妊娠组组内比较,血清ACA和β-HCG水平差异无统计学意义(P>0.05)。病理性妊娠组和正常妊娠组孕妇血清ACA与β-HCG表达均呈正相关性(r=0.458、0.693,P<0.05或0.01)。结论妊娠期间监测高危孕妇血清ACA以及β-HCG水平能早期发现、早期诊断病理性妊娠。
Objective To study the clinical significance of serum levels of ACA and β-HCG in patients with pathological pregnancy. Methods Totally 122 pregnancy women selected from Zhuhai Hospital were divided into normal pregnancy group（n=40） and pathological pregnancy group（n=82）.Serum ACA level was determined by enzyme linked immunosorbent assay（ELISA） and serum β-HCG concentration was detected by electrochemiluminescence immunoassay. Results Serum levels of ACA and β-HCG in pathological pregnancy group were significantly higher than those of normal pregnancy group（P0.05）.No statistically significant difference was found among all the patients with pathological pregnancy（P0.05）.Serum ACA level was positively correlated with serum β-HCG concentration in normal pregnancy group and pathological pregnancy group（r=0.458,r=0.693,P0.05,P0.01）. Conclusions Serum levels of ACA and β-HCG can early predict and diagnose pathological pregnancy.
出处
《实用预防医学》
CAS
2011年第2期284-285,共2页
Practical Preventive Medicine
关键词
病理性妊娠
抗心磷脂抗体
绒毛膜促性腺激素
酶联免疫法
电化学发光免疫法
Pathological pregnancy
Anti-cardiolipin antibodies
β-human chorionic gonadotrophin
Enzyme linked immunosorbent assay
Electrochemiluminescence immunoassay
