摘要
目的 探讨肌钙蛋白T在不稳定型心绞痛中的诊断和预后判断价值.方法 选择98例不稳定型心绞痛（UAP）患者和100例稳定型心绞痛（SAP）患者,分别在入院后0～4 h及12～24 h检测血清肌钙蛋白T（cTnT）水平,并随访其血清cTnT水平与6个月内急性心脏事件发生之间的关系.结果 不稳定型心绞痛患者血清cTnT阳性率明显高于稳定型心绞痛患者[46.9%（46/98）比2%（2/100）],Braunwald 3级者cTnT阳性率（27例,84.4%）高于2级者（16例,47.1%）和l级者（3例,9.4%）,血清cTnT阳性者6个月内急性心脏事件发生率明显高于血清cTnT阴性者[19例比l例].结论 检测血清cTnT水平对于分析不稳定型心绞痛患者的病情严重程度,判断其预后具有重要意义.
Objective To study the diagnostic and prognostic value of troponin T（cTnT） in patients with unstable angina pectoris（UAP）. Methods Totally 98 cases of patients with UAP and 100 cases patients with stable angina pectoris（SAP） were selected, their levels of cTnT were measured respectively at 0-4 hours and 12-24 hours after hospitalization, and the relationship between their cTnT levels and the occurrences of acute heart events within 6 months was observed in follow-up. Results Positive rates of the serum of cTnT in patients with UAP were significantly higher than those in patients with SAP, and those of the serum of cTnT in Braunwald grade 3 were also significantly higher than those in grade 2 and grade 1. The rates of acute heart events in patients with positive cTnT were significantly higher than those with negative cTnT. Conclusion There were an important roles in measuring the serum of cTnT at evaluate the pathogenesis of UAP and its prognostic states.
出处
《中国医药》
2011年第3期257-258,共2页
China Medicine
基金
海南省自然科学基金指导性计划项目（806111）
海南省卫生厅科研立项课题（琼卫2008-37）
