摘要
目的:探讨原发性高血压患者代谢综合征(MS)的发生率及其相关危险因素。方法:对1136例原发性高血压患者依据中华医学会糖尿病分会关于MS的定义进行MS筛查,并对年龄、性别、高血压病程、腹围及胰岛素抵抗指数(HOMA-IR)与MS的发生进行回归分析,统计心血管事件、脑血管事件、肾功能异常等高血压并发症发生率。结果:男性高血压患者MS发生率较女性高(P<0.05);在非MS高血压患者中,女性合并血脂紊乱以及合并高BMI的比率明显高于男性(P<0.01),男性单纯高血压及合并高血糖的比率高于女性(P<0.01);年龄、腹围、空腹血糖、HOMA-IR是高血压患者发生MS的危险因素,而高血压病程、收缩压、舒张压、腰臀比、BMI与MS的发生无关;MS组与非MS组相比,心血管事件及脑血管事件发生的比例均较高(P<0.05)。结论:MS在男性中发病率较高,其发生与年龄、腹围、空腹血糖、HOMA-IR等因素有关,高血压合并MS人群发生心脑血管事件的可能性较大。
Objective： To investigate the incidence of metabolic syndrome （MS） in patients with essential hypertension （EH） and to analyze its characteristics. Methods： A cross-sectional survey was conducted in 1 136 patients with EH. The patients were divided into MS group （217） and non-MS group （919） based on whether they were complicated with MS. Results： The incidence of MS was significantly higher in males than in females （P 〈 0. 05 ）. Age, fasting plasma glucose, HOMA-IR and abdomen circumference were significantly different between MS group and non MS-group. And the incidence of complication created by EH was higher in MS patients. Conclusion： Incidence of MS in males with EH was significantly higher than famales. Much attention should be paid to factors such as age, fasting plasma glucose, abdomen circumference and HOMA-IR to prevent and control MS in patients with EH.
出处
《新医学》
2011年第2期88-90,130,共4页
Journal of New Medicine
关键词
原发性高血压
代谢综合征
危险因素
Essential hypertension
Metabolic diseases
Risk factor
