摘要
目的观察孟鲁司特(平喘药)对儿童支气管哮喘缓解期血清总免疫球蛋白E(IgE)水平的影响。方法支气管哮喘缓解期患儿共60人,分别在服用前及服用孟鲁司特3,6,9个月时,监测血清总lgE水平,观察血清总lgE水平的变化。结果孟鲁司特可使血清总lgE水平下降,在服用6,9个月时,血清总lgE水平下降明显,差异具有显著性意义。结论孟鲁司特能有效降低支气管哮喘儿童血清总IgE水平,并能在一定程度上减少哮喘急性发作的次数,预防并控制了哮喘。
Objective To observe the effect of montelukast（a kind of leukotriene receptor antagonist,goods name： singulair,Merck offers） on serum total immunoglobulin E（IgE） of childhood bronchial asthma remission.Methods Patients with a total of 60 cases,who are monitored lgE level before taking montelukast and taking on March,June,September,to observe the changes of serum total lgE.Results Montelukast can make the level of serum total IgE decline,the decline significantly in June and September,there is a significant difference.Conclusion Montelukast can effectively reduce serum total IgE of asthma patients,and can reduce asthma,prevent and control the asthma on a certain extent.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2011年第2期89-91,共3页
The Chinese Journal of Clinical Pharmacology
