摘要
川崎病是一种主要发生于儿童的非特异性全身性血管炎性综合征,迄今病因未明,病变可累及全身中、小血管,特别是冠状动脉,可发生冠状动脉狭窄、血栓形成,导致缺血性心脏病、心肌梗死及猝死,威胁患儿长期生活质量及寿命,在一些发达国家,该病已超过风湿热成为儿童后天性心脏病的首位病因。在此就川崎病冠状动脉损害的诊断及治疗的最新进展予以综述。
Kawasaki disease is nonspecific systemic vasculitic syndrome that mainly afflicts children.The etiology of Kawasaki remains unknown.The disease involves systemic medium and small blood vessels.It is noted that coronary artery lesions are subject to coronary artery stenosis and thrombosis,further leading to ischemic heart disease,myocardial infarction,and sudden death.Kawasaki disease has been threatening the quality of life and life expectancy of children,whereas in some developed countries,it has been the leading cause of pediatric acquired heart disease,surpassing rheumatic fever.This article reviews the recent progress in the diagnosis and treatment of coronary artery lesion in Kawasaki disease.
出处
《医学综述》
2011年第3期383-386,共4页
Medical Recapitulate
关键词
川崎病
冠状动脉损害
冠状动脉瘤
Kawasaki disease
Coronary artery lesion
Coronary aneurysms
