DNA甲基化与儿童白血病的临床研究进展
被引量:3
摘要
DNA甲基化是研究最广泛的哺乳动物表观遗传学修饰,它提供了一种稳定的可遗传的基因沉默机制,与组蛋白修饰和其他的染色质相关蛋白一起,在调节基因表达和染色体结构方面起重要作用。DNA甲基化是指在DNA甲基转移酶(DNA methyl-transferases,DNMT)的作用下,
出处
《中国当代儿科杂志》
CAS
CSCD
北大核心
2011年第2期174-176,F0003,共4页
Chinese Journal of Contemporary Pediatrics
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