摘要
目的:分析人工流产术后并发闭经患者的临床特点。方法:回顾性分析我院近5年来人工流产术后并发闭经患者的临床资料,记录性激素检查情况、宫腔镜检查结果、以及诊断性刮宫病理学检查结果,同时记录其治疗预后。结果:5年来我院共发生人流后闭经37例,占总人流患者的1.4%。发生距人流时间2~16个月,闭经时间2~5个月。人流次数越多,越易发生(χ2=13.440,P=0.001);是否生产和术后闭经无关(χ2=0.037,P=0.847)。性激素检查显示卵巢早衰者或下丘脑功能失调性闭经共8例(21.6%)。宫腔镜检查显示宫颈内口粘连11例(29.7%),宫腔粘连18例(48.6%)。刮出物中有炎性细胞浸润者占64.0%。经过积极治疗,35例患者恢复周期,另2例效果不佳。结论:人工流产术可能导致一定的术后闭经并发症发生;宫颈内口和宫腔粘连以及性激素异常是造成术后闭经的主要原因,而炎症反应在其中也可能起到一定的作用;人工流产术后闭经治疗预后尚可。
Objective:To analyze the clinical characteristics of patients with amenorrhea after induced abortion.Methods:The patients with amenorrhea after induced abortion in our hospital of the past 5 years were analyzed retrospectively.Some characteristics of the patients were recorded,including sex hormone level,results of hysteroscopy,diagnostic curettage pathological Results,as well as prognosis.Results:A total of 37 patients(1.4%) suffered amenorrhea 2 to 16 months after induced abortion,which sustained for 2 to 5 months.The occurrence of amenorrhea was positively related to the frequency of induced abortion(χ2 = 13.440,P = 0.001),but had nothing to do with delivery(χ2 = 0.037,P = 0.847).Sex hormone level revealed premature ovarian failure or hypothalamic amenorrhea dysfunction in 8 patients(21.6%).Hysteroscopic examination revealed 11 patients had cervical adhesions(29.7%),and 18 patients had intrauterine adhesions(48.6%).Inflammatory cells accounted for 64.0% in all scrapings.After active treatment,35 patients resumed menstrual cycle,but the other two patients found it ineffective.Conclusion:The induced abortion may lead to complication like postoperative amenorrhea.Cervical or uterine adhesions,and abnormal sex hormones are the main reasons for amenorrhea,and inflammatory response may also play a role in it.Postoperative amenorrhea may have a good prognosis after treatment.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2011年第1期119-120,共2页
Journal of Chongqing Medical University
关键词
人工流产术
闭经
并发症
induced abortion
amenorrhea
complication