摘要
目的探讨联合检测血清肿瘤标志物CA125、CEA及AFP对卵巢的诊断价值及其意义。方法选择我院卵巢癌患者30例作为卵巢癌组,卵巢良性肿瘤患者30例作为良性肿瘤组,健康体检者30例作为对照组,进行血清CA125、CEA及AFP检测,比较三组CA125、CEA及AFP表达水平的差异,并比较卵巢癌组患者CA125、CEA及AFP单独检测及联合检测的阳性预测值和阴性预测值。结果卵巢癌组血清CA125、CEA及AFP表达水平高于对照组及良性肿瘤组,血清CA125、CEA及AFP联合检测的阳性预测值、阴性预测值高于CA125、CEA及AFP单独检测。结论血清CA125、CEA及AFP联合检测能够提高卵巢癌的诊断特异性,提高卵巢癌检出率。
Objective To investigate the value of combined detecting tumor markers CA125,CEA and AFP in serum for diagnosis of ovadan carcinoma（OC）. Methods Thirty patients were selected and divided into OC groups,30 patients with benign tumor of ovary were selected and divided into benign tumor groups and 30 healthy adult female were selected and divided into control groups.Expressive levels of CA125,CEA and AFP were detected on every groups and expressive disparation was contrasted in three groups, positive predictive value, negative predictive value was contrasted between solitary detecting and combined detecting. Results Expressive of CA125,CEA and AFP in serum level on patients with OC was higher than on patinets with benign tumor and healthy volunteer, positive predictive value and negative predictive value by combined detecting of CA125, CEA and AFP was higher than solitary detecting. Conclusion Combined detecting of CA125, CEA and AFP could improve the diagnostic specificity of OC and improve detection rate .
出处
《中国现代医生》
2011年第3期155-156,共2页
China Modern Doctor
