摘要
目的探讨沙眼衣原体(CT)和解脲支原体(UU)感染与孕妇稽留流产的相关性,以及荧光定量PCR在稽留流产病因检测中的应用价值。方法采用荧光定量PCR检测稽留流产患者宫颈分泌物标本中的CT-DNA和UU-DNA的含量。结果 138例稽留流产患者中72例感染CT或UU,总检出率53.62%,其中CT阳性率21.74%,UU阳性率42.03%,混合感染10.14%。与正常人群对照差异均有统计学意义(P<0.05)。结论泌尿生殖系统CT和UU的感染与稽留流产有密切相关性,荧光定量PCR对稽留流产患者CT和UU的检测简单、快速、准确。
Objective： To investigate the correlation between the infections of Chlaydia Trachomatis （CT） and Ureaplasma Urealyticum （UU） and the occurrence of the missed abortion in pregnant women,and discuss the meaning of diagnosis missed abortion using fluorescent quantitative PCR （FQ-PCR）.Methods： Detecting content of CT-DNA and UU-DNA in missed abortion patients＇ cervical secretions by FQ-PCR.Results： There are 72 patients infected by CT or UU in all of 138 cases with missed abortion.The total detection rate is 53.62% ,of which CT-positve rate is 21.74% ,UU-positve rate is 42.03% ,and mixed infection is 10.14%.The results are statistically significant differences with the normal population controls （P〈0.05）.Conclution： Infections of CT and UU in genitalduct are closely related with missed abortion,and detection of CT and UU in patients with missed abortion by FQ-PCR is simple,fast and accurate.
出处
《中国优生与遗传杂志》
2011年第1期19-20,共2页
Chinese Journal of Birth Health & Heredity
关键词
稽留流产
沙眼衣原体
解脲支原体
荧光定量PCR
Missed Abortion
Chlaydia Trachomatis
Ureaplasma Urealyticum
Fluorescent Quantitative PCR
