摘要
目的：探讨子宫腺瘤样瘤的组织发生、临床病理特点及鉴别诊断。方法：对46例子宫腺瘤样瘤进行临床病理及免疫组织化学观察。结果46例子宫腺瘤样瘤占同期子宫标本的1．91％，肿瘤位于子宫肌壁间或浆膜下，直径0．3—5．4cm，临床表现无特征性。铝k下肿瘤有大小不等，形态不一的腺腔样结构组成，周围可见增生的平滑肌细胞。免疫组织化学染色显示CKpan、Calretinin、MC、Vimendn阳性，ER、PR、CEA、CD31、CD34、D2-40阴性。结论：子宫腺瘤样瘤为间皮起源，免疫组化可作为诊断和鉴别诊断的重要参考依据，其生物学行为为良性，预后良好。
Objective ：To study the histogensis the clinicopathological characteristics and the differential diagnosis of adenomatoid tumors in uterus. Methods：Clinical pathological analysis and immunohislochemical sludies were performed on 46 cases of adenomaloid lumors in the uterus and ovaries.Resuhs ：46 cases of uterine adenomatoid tumor were diagalosed accounting for 1.91% of all hysterectomy for same period.The tumors were located in the uterine muscle walls or under serosa.The masses ranged from 0.3 to 5.4 cm in size.The clinical characteristics were not appearant.Histologically, the tumor was composed of gland like structure with variable size and in＇egular morphology, surrounded by proliferative smooth muscle cells. Immunohistochemical staining showed the tumor cells positive for CKpan ,Calretinin ,MC ,Vimentin, but negative for ER ,PR ,CEA, CD31 ,CD34 ,D2-40. Conclusion：Adenomatoid tumor of uterus is mesothelial in origin, hnmunohistochemcal phenotypes can be used as an important evidence for differential diagnosis. The biological behavior of adenomatnid tumor is benign with a good prognosis.
关键词
子宫腺瘤样瘤
免疫组化
诊断与鉴别诊断
Adenomatoid turmor of uterus
Immunohistochemistry
Diagnosis and differential diagnosis
