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重症肺炎患者心肌酶的改变及临床意义 被引量:7

Clinical study on myocardial enzymes change of patients with severe pneumonia in ICU
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摘要 目的观察重症监护病房重症肺炎患者血清心肌酶水平变化及临床意义。方法60例重症肺炎患者(简称重症肺炎组)和58例普通肺炎患者(简称肺炎组)为研究对象,另选择同期健康体检正常者60例为对照组。入选对象均采用全自动生化分析仪行肌酸激酶同工酶、肌酸激酶、α-羟丁酸脱氢酶、谷草转氨酶检查。结果重症肺炎组心肌酶各项指标均显著高于肺炎组和对照组,差异均有统计学意义(均P〈0.05);肺炎组与对照组比较,血清心肌酶各项指标差异均无统计学意义(均P〉0.05);重症肺炎组有效率为96.7%,2例无效患者均在治疗期间死亡;肺炎组临床疗效有效率为100.0%,无死亡发生。结论重症肺炎患者存在心肌损害,心肌酶可作为诊断依据和判断预后的有效指标。 Objective To observe the clinical significance of myocardial enzymes change of patients with severe pneumonia in intensive care unit ( ICU ). Methods 60 patients with severe pneumonia ( severe pneumonia group) and 58 patients with ordinary pneumonia( pneumonia group) were studied, and 60 healthy subjects were studied as normal control group. The CK-MB, CK, HBDH and AST levels of the research objects were analyzed by automatic chemistry analyzer. Results The enzyme indicators of severe pneumonia group were higher than the pneumonia group and normal control group, compared with the pneumonia group and normal control group, the differences were significant( all P 〈 0. 05 ) ; The enzyme indicators of the pneumonia group compared with normal control group the difference was not significant (P 〉 0. 05 ). The effective rate of severe pneumonia was 96.7% ,ineffective 2 cases died in the treatment. The effective rate of pneumonia group was 100.0%, and no deaths occurred. Conclusion There was myocardial damage in patients with severe pneumonia, myocardial enzyme could be used as a valuable indicator for diagnosis, observing tendency, and predicting prognosis of patients with severe pneumonia in ICU.
作者 李永春
出处 《中国基层医药》 CAS 2011年第3期315-316,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 重症监护病房 重症肺炎 心肌酶谱 Intensive care unit Severe pneumonia Myocardial enzymes
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