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右美托咪啶预防芬太尼引起呛咳反应的临床研究 被引量:18

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摘要 目的:观察和评价预输注右美托咪啶预防芬太尼引起呛咳反应的效果。方法:60例ASAⅠ~Ⅱ级患者随机分为观察组(A组)和对照组(B组)。A组麻醉诱导前静脉缓慢泵注(10min)右美托咪啶1μg/kg,B组泵注等量的生理盐水,泵注结束后两组均在3s内快速静脉推注芬太尼4μg/kg,观察芬太尼引起的呛咳反应发生率和程度、诱导前后血流动力学的变化。结果:AB两组患者呛咳的发生率分别为23.3%、56.7%(P<0.01),呛咳强度明显减弱(中重度呛咳发生率分别为2/30和8/30,P<0.01)。B组插管前血压低于A组,插管后1min时B组血压、心率高于A组。结论:右美托咪啶能够预防芬太尼引起呛咳反应,并能维持血流动力学的稳定。
出处 《实用医学杂志》 CAS 北大核心 2011年第4期671-672,共2页 The Journal of Practical Medicine
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参考文献11

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二级参考文献9

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