摘要
目的了解该地区精神病患者乙型肝炎病毒表面抗原(HBsAg)和丙氨酸氨基转移酶(ALT)阳性情况,为医院有效控制肝炎在精神病患者中的传播提供依据。方法对1365例精神病患者和997例健康体检者采用酶联免疫吸附试验(ELISA)法检测HBsAg、采用连续检测比色法检测ALT。结果精神病患者HBsAg阳性率为19.56%,ALT阳性率为10.84%,与健康对照组比较,差异均有统计学意义(P<0.05);在不同性别中,HBsAg男性阳性率(25.75%)高于女性阳性率(14.68%)。ALT男性阳性率(14.45%)高于女性阳性率(7.99%),男、女比较差异有统计学意义(P<0.05)。结论精神病患者HBsAg和ALT阳性率均高于普通人群,对这类患者应采取监测、隔离、治疗等措施,防止乙型肝炎病毒(HBV)的传播感染,同时也有利于患者的康复。
Objective To understand the positive status of hepatitis B virus surface antigen（HBsAg） and alanine aminotransferase（ALT） in the patients with mental diseases in Luzhou area to provide the basis for the effective control of hepatitis spreading in the mental hospital patients.Methods HBsAg was detected by enzyme-linked immunosorbent assay（ELISA） and ALT by continuous detection colorimetric method in 1 365 cases of mental patients and 997 healthy subjects.Results The positive rate of HBsAg in psychiatric patients was 19.56% and the positive rate of ALT was 10.84%,showing statistical significance compared with the healthy control group（P0.05）.In different genders,the positive rate of HBsAg in males（25.75%） was higher than that in females（14.68%）.The positive rate of ALT in males（14.45%） was higher than that in females（7.99%）,the difference was statistically significant between males and females（P0.05）.Conclusion The positive rates of HBsAg and ALT in mental patients all are higher than those in general population,these patients should be taken monitoring,isolation and treatment measures to prevent the transmission of hepatitis B virus（HBV） infection,which is conducive to rehabilitation of patients.
出处
《检验医学与临床》
CAS
2011年第3期278-279,共2页
Laboratory Medicine and Clinic
