摘要
目的分析早发ST段抬高型急性心梗(STEMI)患者的传统危险因素分布以及血生化指标及冠状动脉造影结果特点。方法收集自2009年1月-2010年3月STEMI临床资料,比较早发STEMI患者(男性<55岁,女性<65岁)和非早发的STEMI患者(男性>55岁,女性>65岁)的传统危险因素、血生化代谢指标及冠脉造影结果的差异,并进行统计学分析。结果早发STEMI组与非早发组比较具有以下临床特点:吸烟(56.8%∶38.0%,P<0.05)和代谢综合征(55.6%∶33.0%,P<0.05)的比率较高。早发STEMI组的体重指数(BMI)显著高于非早发组[(25.94±3.15)∶(24.75±3.66)P<0.05]。早发组以冠脉单支病变为主(58.0%∶31.0%,P<0.05),以前降支受累为主,而非早发组以三支病变为主(21.0%∶44.0%,P<0.05)。针对早发STEMI危险因素的Logistic多元回归分析发现代谢综合征和吸烟是早发STEMI的独立危险因素,代谢综合征和吸烟的OR值分别是2.54和2.82。结论吸烟和代谢综合征在早发STEMI的发生、发展过程中起重要作用,对于存在代谢异常的青中年患者进行减肥和戒烟具有尤其重要的预防心血管事件的意义。
Objective To analyze the distribution of traditional risk factors and biochemical indicators in patients with premature acute ST-elevated myocardial infarction（STEMI） and the clinical characteristics of coronary arteriography.Methods Clinical data（including traditional risk factors,biochemical indicators and coronary arteriography） about patients with premature and non-premature STEMI were collected and comparatively analyzed.Results The rates of smoking,metabolic syndrome and body mass index（BMI） were higher in patients with premature STEMI than in those with non-premature STEMI（56.8% vs 38.0%,55.6% vs 33.0%,25.94±3.15 vs 24.75±3.66,P0.05）.The rate of lesions involving asingle coronary branch was higher in patients with premature STEMI than that of lesions involving three coronary branches in those with non-premature STEMI（58.0% vs 31.0%,21.0% vs 44.0%,P0.05）.Logistic regression showed that smoking and metabolic sydrome were the independent risk factors for premature acute myocardial infaction with an OR value of 2.54 and 2.82,respectively.Conclusion Smoking and metabolic sydrome play an important role in occurrence and progression of premature acute myocardial infaction.Weight reduction and smoke abatement are of great importance for reducing the occurrence of cardiovascular events in middle-aged and young patients with metabolic sydrome.
出处
《军医进修学院学报》
CAS
2011年第2期133-135,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
心肌梗死
危险因素
代谢综合征
Myocardial Infaction
Risk Factors
Metabolic Syndrome
