摘要
目的：评价针灸治疗溃疡性结肠炎的临床随机对照试验的质量。方法：电子检索CBM、中国知网、维普、万方等数据库,广泛收集相关文献,按照临床流行病学和循证医学的原则和方法,对1978年1月~2010年4月发表的临床随机对照试验的研究类型及方法学、一般情况、疾病诊断及纳入和排除标准、盲法、分配隐藏、疗效判定标准、随访、不良反应等方面进行评价。结果：符合标准的文献共50篇,其中描述具体随机方法的有8篇;半随机对照试验7篇;随机字样35篇;运用盲法的3篇;采用诊断标准有42篇;有疗效判定标准的49篇;有随访记录的10篇。纳入文献均没有分配隐藏的描述和样本量的估算。结论：针灸治疗溃疡性结肠炎的临床随机对照试验研究文献的质量有待提高,目前迫切需要正确实施随机、隐藏及盲法、安慰剂对照、有公认诊断及疗效评价标准、进行安全性评价、合理设计随访的随机对照试验。
Objective：To evaluate the quality of randomized controlled trials（RCTs） on acupuncture and moxibustion for Ulcerative Colitis and carries on the method to study the quality evaluation to all randomized controlled trials.Methods：The literatures between 1978.01-2010.04 were searched by means of electronic retrieval.Type and methodology,general condition,diagnosis of diseases and enrolled and excluded criteria,assessment of sample content,treatment condition,criteria for assessment of therapeutic effects,following-up,etc.in clinical studies are evaluated according to principles and methods of clinical epidemiology and evidence-based medicine.Results：Of the 50 literatures enrolled,only 8 were authentic randomized controlled trials（RCTs）;7 quasi-randomized controlled trials;42 had clear diagnostic criteria;49 had clear criteria for therapeutic effects;10 reported follow-up;5 reported adverse reaction.Conclusion：The quality of RCT papers relevant to acupuncture and moxibustion for Ulcerative Colitis needs improving.At present,correct randomization,concealment,blinding and placebo-control,and the RCTs with generally accepted criteria for assessment of diagnosis and therapeutic effects,safe evaluation and rational design of follow-up are needed.
出处
《针灸临床杂志》
2011年第1期6-9,共4页
Journal of Clinical Acupuncture and Moxibustion
基金
国家"十一五"科技支撑计划项目
编号:2006BAI12B01
关键词
针灸
溃疡性结肠炎
随机对照试验
质量评价
Acupuncture and moxibustion
Ulcerative Colitis
Quality evaluation
