期刊文献+

门诊口服质子泵抑制剂不合理用药处方分析 被引量:6

下载PDF
导出
摘要 目的了解该院门诊口服质子泵抑制剂(proton pump inhibitor,PPI)不合理用药处方的情况,以提高医务人员合理用药水平。方法 抽取2010年1-3月含口服PPI的处方1981张,从中挑选出不合理用药处方进行归类分析。结果 抽查的1981张处方中不合理用药处方191张,不合格率为9.64%。不合理用药发生频率较高的是药物配伍不合理(影响药物的吸收、代谢,不良反应增加等)、药物用法不合理等。结论 该院口服PPI存在一定程度的不合理用药现象,应不断提高医护人员、药学工作者合理用药水平。
出处 《临床合理用药杂志》 2011年第1期123-124,共2页 Chinese Journal of Clinical Rational Drug Use
  • 相关文献

参考文献2

二级参考文献9

  • 1Sakai T,Aoyama N,Kita T,et al.CYP2C19 genotype and phar-macokinetics of three proton pump inhibitors in healthy subjects[J].Pharmres,2001,18:721-727. 被引量:1
  • 2Lind T,Rydberg L,Kyleback A,et al.Esomeprazole provides im-proved acid control vs.omeprazole In patients with symptoms of gastro-oesophageal reflux disease[J].Aliment Pharmacol Ther,2000,14(7):861-867. 被引量:1
  • 3Kanazawa H,Okada A,Higake M,et al.Stereospecific analysis of omeprazole in human plasma as a probe for CYP2C19 phenotype[J].Pharm Anal,2003,30(6):1817-1827. 被引量:1
  • 4Welage LS,Berardi RR.Evaluation of Omerprazole,Lansoprazo-le,Pantoprazole,in the trement of acid-related disease[J].Jam Pharm Assoe Wash,2000,40(1):56-62. 被引量:1
  • 5Inaba T,Mizuno M,KawaiK,et al.Randomized open trial for co-mparison of proton pump inhibitors in triple therapy for Helicobacter pylori infection in relation to CYP2C19 genotype[J].Gastroenterol Hepatol,2002,17(7):748-753. 被引量:1
  • 6Richter JE,Kahrilas FJ.Johanson J,et al.Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis:a randomized controlled trial[J].Gastroenterol,2001,96(3):656-665. 被引量:1
  • 7Abelo A,Andersson TB,Antonsson M,et al.Stereoselective me-tabolism of omeprazole by human cytochrome P450 enzymes[J].Drug Metab Dispos,2000,28(8):966-972. 被引量:1
  • 8Shih H,Pickwell GV,Guenette DK,et al.Species differences in hepatocye induction of CYP1A1 and CYP1A2 by omeprazole[J].Hum Exp Toxicol,1999,18(2):95-105. 被引量:1
  • 9孙培红,鲁云兰.质子泵抑制剂的药理作用及临床应用[J].中国医院用药评价与分析,2003,3(3):180-184. 被引量:39

共引文献13

同被引文献65

  • 1朱珠,蔡乐.质子泵抑制剂的安全性与合理应用[J].药物不良反应杂志,2005,7(2):81-90. 被引量:56
  • 2季代金,黄茂涛,余宁,赵悦,陈勇.NERD患者埃索美拉唑联合莫沙必利与加强生活方式干预对照研究112例[J].世界华人消化杂志,2007,15(14):1650-1653. 被引量:2
  • 3Yi-fan ZHANG,Xiao-yan CHEN,Xiao-jian DAI,Yi-ni ZHANG,Qi-zhi LIU,Hua-ling YU,Da-fang ZHONG.Influence of omeprazole on pharmacokinetics of domperidone given as free base and maleate salt in healthy Chinese patients[J].Acta Pharmacologica Sinica,2007,28(8):1243-1246. 被引量:2
  • 4王寒明 王怀良.PPI与氯吡格雷-药学专家有话说.临床合理用药杂志,2010,:19-19. 被引量:2
  • 5Ito T, Jensen RT. Association of long-term proton pump inhibitor ther- apy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium [J]. Curr Gastroenterol Rep, 2010, 12 (6) :448. 被引量:1
  • 6Howell MD, Novack V, Grgurich P, et al. latrogenic gastric acid sup- pression and the risk of nosocomial elostridium difficile infection [ J ]. Arch Intern Med,2010,170 (9) :784. 被引量:1
  • 7van der Pol RJ,Smits MJ,van Wijk MP. Efficacy of proton-pump inhibitors in children with gastroesophageal reflux disease:a systematic review[J].PEDIATRICS,2011,(05):925-935. 被引量:1
  • 8Ito T,Jensen RT. Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium,vitamin B12,iron,and magnesium[J].Current Gastroenterology Reports,2010,(06):448.doi:10.1007/s11894-010-0141-0. 被引量:1
  • 9Targownik LE,Lix LM,Metge CJ. Use of proton pump inhibitors and risk of osteoporosis-related fractures[J].Canadian Medical Association Journal,2008,(04):319-326.doi:10.1503/cmaj.071330. 被引量:1
  • 10He PM,Maddox TM,Wang L. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome[J].Journal of the American Medical Association,2009,(09):937.doi:10.1001/jama.2009.261. 被引量:1

引证文献6

二级引证文献36

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部