期刊文献+

帕罗西汀联合利培酮治疗慢性膝关节痛疗效观察

原文传递
导出
摘要 目的 探讨帕罗西汀联合利培酮治疗慢性膝关节疼痛的疗效. 方法 采用随机法将80例慢性膝关节痛患者分研究组和对照组,两组分别予以帕罗西汀合并利培酮、氯诺昔康治疗. 结果 在48 h评估时对照组疼痛视觉模拟评分(VAS)(2.78±0.77)分低于研究组(3.74±0.99)分(P<0.05),14 d和21 d时VAS(2.67±0.65与3.36±0.91;2.48±0.92与3.45±1.04)、Beck抑郁问卷(BDI)(24.60±9.45与31.52±11.05;21.89±12.09与33.78±12.35)、焦虑自评量表(SAS)(22.88±9.01与30.55±6.99;21.30±10.55与31.55±9.50)评分均表现为研究组低于对照组(均P<0.05),而其它各时段两组之间各量表评估差异无统计学(均P<0.05). 结论 帕罗西汀联合利培酮治疗慢性膝关节疼痛具有较好疗效.
作者 徐光洪
出处 《中国基层医药》 CAS 2010年第23期3250-3251,共2页 Chinese Journal of Primary Medicine and Pharmacy
  • 相关文献

参考文献6

二级参考文献19

  • 1HongZhao,Tie-huYe,Zhi-yiGong,YangXue,Zhang-gangXue,Wen-qiHuang.APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES[J].Chinese Medical Sciences Journal,2005,20(1):59-62. 被引量:26
  • 2马加海,徐礼鲜,张国良,卢玲玲,徐瑞芬,李源,王惠霞.舒芬太尼、芬太尼用于颌面外科术后镇痛的对比观察[J].中国疼痛医学杂志,2005,11(3):154-156. 被引量:28
  • 3Corruble E,Guelfi JD. Pain complaints in depressed inpatients. Psychopathology, 2000,33 (6): 307-309. 被引量:1
  • 4Baune BT,Caniato RN,Garcia-Alcaraz MA,et al. Combined effects of major depression,pain and somatic disorders on general functioning in the general adult population. Pain,2008,138(2): 310-317. 被引量:1
  • 5Goncalves L,Silva R,Pinto-Ribeiro F,et al. Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat Exp. Neurol, 2005,213 ( 1 ): 48-56. 被引量:1
  • 6Zeng Q,Wang S,Lim G,et al. Exacerbated mechanical allodynia in rats with depression-like behavior. Brain Res, 2008,1200: 27- 38. 被引量:1
  • 7Andre J,Zeau B,Pohl M, et al. Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: behavioral and hi.heroical studies. J Neurosci ,2005,25 (35): 7896- 7904. 被引量:1
  • 8Csemansky JG,Sheline YI. Abnormalities of serotonin metabolism and nonpsychotic psychiatric disorders. Ann Clin Psychiatry, 1993,5(4): 275-281. 被引量:1
  • 9Mann JJ,Malone KM. Cerebrospinal fluid amines and higher- lethality suicide attempts in depressed inpatients. Biol Psychiatry. 1997,41(2): 162-171. 被引量:1
  • 10Singh VP, Jain NK,Kulkami SK. On the antinociceptive effect of fluoxetine,a selective serotonin reuptake inhibitor. Brain Res, 2001,915(2): 218-226. 被引量:1

共引文献2914

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部